Nampt-IN-1 - CAS 1698878-14-6
Catalog number:
1698878-14-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H25N3O5S
Molecular Weight:
419.49
COA:
Inquire
Targets:
Nampt
Description:
Nampt-IN-1, a pyridyloxyacetyl tetrahydroisoquinoline compound, is a novel inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with the potential to treat cancer. IC50: NCI-H1155 cell= 18 nM, Calu-6 cell= 49 nM, HCC1937 cell= 333 nM, MCF-7 cell= 3
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Appearance:
White to off-white Solid
Synonyms:
2-hydroxy-2-methyl-N-[2-(2-pyridin-3-yloxyacetyl)-3,4-dihydro-1H-isoquinolin-6-yl]propane-1-sulfonamide Nampt-IN-1 CHEMBL3586462 SCHEMBL16634738
Solubility:
DMSO: ≥ 45 mg/mL
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -77℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
659.9±65.0 °C | Condition: Press: 760 Torr
Density:
1.363±0.06 g/cm3
InChIKey:
QHHSCLARESIWBH-UHFFFAOYSA-N
InChI:
1S/C20H25N3O5S/c1-20(2,25)14-29(26,27)22-17-6-5-16-12-23(9-7-15(16)10-17)19(24)13-28-18-4-3-8-21-11-18/h3-6,8,10-11,22,25H,7,9,12-14H2,1-2H3
Canonical SMILES:
CC(C)(CS(=O)(=O)NC1=CC2=C(CN(CC2)C(=O)COC3=CN=CC=C3)C=C1)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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