|Description||Namiteca is a new water-soluble camptothecin analogue as a hydrophilic camptothecin with a promising preclinical profile.|
|Synonyms||ST 1968; (4S)-11-((E)-((2-Aminoethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Application||DNA topoisomerase I inhibitors|
|Quality Standard||Enterprise standard|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.|
|Current Developer||sigma-tau SpA|
Glafenine hydrochloride, an anthranilic acid derivative, is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor (IC50= 3...
Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. It is a drug for the amelioration of transthyretin-relat...
PD 138142 is a water soluble Sterol O-acyltransferase inhibitor. Triacylglycerol secretion is decreased in the presence of PD-138142-15. Preclinical development...
Amoxapine is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a trans...
Brefeldin A is a fungal metabolite and blocks the forward transport between the endoplasmic reticulum and Golgi apparatus, Brefeldin A causes an impaired distri...
Trichloromethane is a solvent, as a powerful blister agent used for chemical warfare.
Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.
Glucagon, a peptide compound, is effective in increasing the glucose concentration in bloodstream and could be released by pancrea α cells.
BMS-214662 mesylate is a potent and selective inhibitor of farnesyltransferase that induces mitochondrial apoptosis in chronic myeloid leukemia stem/progenitor ...
PF 4693627 is a potent, selective and orally bioavailable inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) that has the potential to treat inflamma...
RS 16566 dihydrochloride
RS 16566 dihydrochloride was found to be a high affinity ligand for the (R)- zacopride binding site (pKi 9.84).
Enprofylline, a xanthine derivative, is a a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine rec...
ONO3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo. It could play an important role in the pathogenes...
Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
GYY-4137 Morpholine salt
GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury...
10-Deacetylbaccatin-III is an antineoplastic agent and an anti-cancer intermediate.
CGP 23996 is a non-reducible somatostatin analog. It can be used for autoradiography.
Imidazole, a highly polar compound, has been used extensively as a corrosion inhibitor and a buffer in the pH range of 6.2-7.8.
CFI-401870, an azabicyclo derivative, has been found to be a TTK inhibitor that could be significant in anticancer studies. IC50 < 10 nM.