|Description||Naltrindole hydrochloride is a cell permeable, potent and highly selective non-peptideδ opioid receptor antagonist (Ki= 0.02 nM) with 223- and 346-fold greater activity at δ than at μ and κ opioid receptors..|
|Brife Description||A highly potent and selective non-peptide δ opioid receptor antagonist (Ki= 0.02 nM)|
|Synonyms||(4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, monohydrochloride; Naltrindole (hydrochloride)|
|Solubility||DMSO: ≥188 mg/mL|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
LY-2456302, also called as CERC-501, is a potent, highly selective and centrally-penetrant kappa opioid receptor antagonist(Ki= 0.807 nM)with favorable pharmaco...
Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and ...
6 α-naloxol, a human metabolite of naloxone, is an opioid antagonist.
Bevenopran is a peripherally selective μ- and δ-opioid receptor antagonist. It is used for the treatment of chronic opioid-induced constipation. It was develope...
Meptazinol is a unique centrally active opioid analgesic, which inhibits [3H]-dihydromorphine binding with IC50 of 58 nM.
Nalfurafine is a selective and centrally-penetrant κ-opioid receptor (KOR) agonist without significant activity on μ- and δ-opioid receptors. With antipruritic ...
Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.
LY 106737 is phenylpiperidine opioid receptor antagonist, but no detailed information has been published yet.
Endomorphin 1 is a high affinity (Ki = 360 pM) and highly selective agonist of theμ-opioid receptor with 4000- and 15000-fold preference over δ and κ respective...
Alvimopan dihydrate is a novel, orally available peripherally restricted opioid antagonist with low systemic absorption. It accelerates the gastrointestinal rec...
LY2795050, a κ-opioid Receptor antagonist, has been found to be effective in imaging KOR behaving as a PET tracer. IC50: 0.72 nM and 25.8 nM for κ-opioid Recept...
Nociceptin, a 17 amino acid neuropeptide involved in a variety of biological systems, is the endogenous ligand of the nociceptin receptor, acting as a potent an...
Naloxegol oxalate is a CYP3A4 enzyme inhibitor, is a peripherally-selective opioid antagonist, for the treatment of opioid-induced constipation.
[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.
Nor-Binaltorphimine dihydrochloride is a potent and selective kappa opioid receptor antagonist.
LY 123502 is an opioid agonist, but no detailed information has been published yet.
Enadolineis a potent selective Opioid kappa receptor agonists originated by Pfizer. However, clinical trials for the treatment of Arrhythmias, Neuroprotection a...
GSK-1521498 is a novel μ-Opioid receptor antagonist. It shows to attenuate reward-driven compulsive behaviours, such as stimulant drug seeking or binge eating i...
ADL5859 HCl is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel.
Dermorphin, a naturally occurring heptapeptide originally found in the skin of amphibians, is a μ-opioid receptor(MOR) agonist with analgesic and antinociceptiv...