|Description||Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.|
|Related CAS||65472-88-0 (Free base)|
|Synonyms||(E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochloride; AW 105843; AW105843; AW-105843; AW 105-843; SN 105843; SN105843; SN-105843; Naftifine, Naftifine hydrochloride; Naftin|
Natamycin is a naturally occurring antifungal agent produced during fermentation by the bacterium Streptomyces natalensis with a MIC (minimum inhibitory concent...
L-4-oxalysine is a natural product isolated from a new species of Streptomyces roseoÍiridofuscus n.sp. in China. L-4-oxalysine inhibits the proliferation of som...
Exalamide is a derivative of salicylamide used as an antifungal.
Bifonazole is an imidazole antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form.
Cercosporamide, a natural antifungal phytotoxin, has been found to be a selective Mnk inhibitor and shows probable antileukemic effects.
2,4,6-Tribromophenyl caproate is an anti-fungal agent.
Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall...
Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. It is used primarily to treat fun...
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema. Climbazole has shown a high...
GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus.
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infect...
The combination of Flucytosine and IgGl monoclonal antibody to Cryptococcus neoformans capsular glucuronoxylomannan is more effective in reducing the numbers of...
Flumorph did not inhibit the synthesis of cell wall materials, but disturbed the polar deposition of newly synthesized cell wall materials during cystospore ger...
Tavaborole (AN2690) is a potent antifungal that targets the post-transfer editing site of leucyl-tRNA synthetase (LeuRS). Tavaborole forms a covalent adduct wit...
Propoxur, a carbamate derivative, could be widely used as an insecticide against sorts of agricultural pests.
Sulbentine is an antifungal.
Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol, used in the treatment and prevention of s...
(+)-Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligos...
Hexetidine, mixture of stereoisomers, is an antibacterial and antifungal agent that destroy fungi by suppressing their ability to grow or reproduce.
Itraconazole, a triazole antifungal agent, is a relatively potent inhibitor of CYP3A4.