|Description||N6-(4-Hydroxybenzyl)adenosine, an imidazopyrimidine derivative, could be effective as an inhibitor of platelet aggregation. IC50: 6.77-141 μM.|
|Synonyms||N6-(4-Hydroxybenzyl)-adenosine; 110505-75-4; N6-(4-hydroxybenzyl)adenine riboside; N6-(4-hydroxybenzyl)adenosine; CHEMBL224024; P-Topolin riboside|
|Solubility||DMSO：≥ 3.8 mg/mL|
|Application||N6-(4-Hydroxybenzyl)adenosine, an imidazopyrimidine derivative, could be effective as an inhibitor of platelet aggregation.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
αβ-methylene ATP, a phosphonic analog of ATP, is an agonist of P2X purinoceptors P2X1 and P2X3 (EC50 = ~1 µM) and is ~1,000-fold less potent at P2X2, P2X recept...
PIT selectively and non-competitively blocked P2Y1 receptor signaling without affecting nucleotide binding. PIT had no significant effect on agonist activation ...
AR-C 66096 tetrasodium salt
The sodium salt form of AR-C 66096, which has been found to be a P2Y12 receptor antagonist and could be probably used as an antithrombotic agent.
MRS 2905 is a potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM), with >2000-fold selectivity over P2Y6.
The sodium salt of Suramin which is a P2 purinergic antagonist and has been also found to have the effect in blocking the G protein binds to GPCRs so that it wa...
MRS 2693 trisodium salt
MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor), with no activity at other P2Y subtypes.
Clopidogrel is converted to its active metabolite by cytochrome P450 (CYP) enzymes.
2-ThioUTP tetrasodium salt
2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist (EC50 = 0.035, 0.35 and 1.5 μM for hP2Y2, hP2Y4 and hP2Y6 receptors, respectively).