N3PT - CAS 13860-66-7
Catalog number:
13860-66-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C13H19Cl2N3OS
Molecular Weight:
336.28
COA:
Inquire
Targets:
Others
Description:
N3PT inhibits transketolase activity in a cell based assay. Competitive inhibition of TK by N3PT in cells treated with increasing doses of thiamine, expressed as percentage enzymatic activity (the slope of initial linear range) of controls not treated with compounds. Tumors were induced in mice at day 0 and mice were then treated at day 7 with vehicle alone or with N3PT [2]. Low-thiamine diet enhances the sensitivity to N3PT inhibition of TK in spleen. Animals were switched to diets containing 16.5 mg/kg (unchanged), 5 mg/kg, 1 mg/kg, or 0 mg/kg thiamine, from a normal chow containing 16.5mg/kg thiamine.
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Purity:
>98%
Synonyms:
N3-pyridyl thiamine
MSDS:
Inquire
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CAS 13860-66-7 N3PT

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