N-Despropyl-macitentan - CAS 1103522-45-7
Catalog number:
1103522-45-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C16H14Br2N6O4S
Molecular Weight:
546.19
COA:
Inquire
Targets:
Endothelin Receptor
Description:
N-Despropyl-macitentan, an active metabolite of Macitentan, is a dual ET receptor antagonist with longer half-life than Macitentan. It has been proved to be effective in the treatment of ulmonary arterial hypertension.
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Purity:
> 95%
Appearance:
Powder
Synonyms:
N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-sulfamide, ACT-132577
Solubility:
DMSO: ≥ 46 mg/mL
Storage:
-20ºC Freeze
MSDS:
Inquire
Application:
N-Despropyl-macitentan is a dual ET receptor antagonist with longer half-life than Macitentan.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
DKULOVKANLVDEA-UHFFFAOYSA-N
InChI:
InChI=1S/C16H14Br2N6O4S/c17-11-3-1-10(2-4-11)13-14(24-29(19,25)26)22-9-23-15(13)27-5-6-28-16-20-7-12(18)8-21-16/h1-4,7-9H,5-6H2,(H2,19,25,26)(H,22,23,24)
Canonical SMILES:
C1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)NS(=O)(=O)N)Br
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