|Description||N-Desmethyl Regorafenib is a metabolite of Regorafenib. Regorafenib is useful for the treatment of inflammation and as an anti-proliferative agent.|
|Synonyms||BAY751098; Regorafenib metabolite M4;UNII-58I22S7HYD;4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide|
|Solubility||Soluble in DMSO|
|Application||a metabolite of Regorafenib|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
ProINDY, the prodrug form of INDY, is a cell permeable ATP-competitive DYRK1A/B inhibitor.
AZD-4694 is a bio-active chemical compound and is used as a diagnostic imaging agent. It was developed by AstraZeneca.
Epimedin A, a flavonoids natural product extracted from Herbal Epimedium, could increase cardiovascular blood flow, promote hematopoietic function and has poten...
Beclamide is a chlorinated benzylpropanamide that possesses anticonvulsant activity, has been used for the treatment of tonic-clonic seizyres and has sedative p...
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancrea...
TCS PrP Inhibitor 13
TCS PrP Inhibitor 13 is an antiprion agent that inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblast...
YMU1 is a human thymidylate kinase (hTMPK; IC50 value 1.65 µM) inhibitor yet not has inhibitory effect on the activity of purified thymidine kinase 1 (TK1). YMU...
GSK-2262167 is a potent S1P3-sparing and S1P1 agonist and has a potent activity is in a collagen-induced arthritis model as efficacious as fingolimod and show...
4-Allylcatechol is an intermediate to synthetic safrole and was used in a study performed to evaluate the phenolic content, antioxidant and antimicrobial activi...
Exogenous H2S, as we know, has anti-inflammatory effects both in macrophages and in animal models. FW1256 is a slow release H2S dononr and it is much more poten...
Tetrahydrofolic acid is a folic acid derivative. It is a cofactor in many bio-reactions, especially in the metabolism of amino acids and nucleic acids.
Yunaconitine is a highly toxic aconitum alkaloid.
GSK-484, a benzoimidazole derivative, has been found to be an effective reversible PAD-4 inhibitor that could be significant in some inflammation and immune res...
BigLEN (mouse) is a proSAAS-derived neuropeptide that acts as a GPR171 agonist. It regulates food intake in mice, and suppresses the release of glutamate onto p...
FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy.
An inhibitor of 5α-reductase
Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine ...
Gluconate Calcium is an calcium supplement used in crop pesticide formulations and also in the treatment of too little calcium in the blood.
Fludrocortisone, a kind of mineralocorticoid, could be used against cerebral salt wasting syndrome for behaving the role as a anti-inflammatory agent.
AP-24600 is a bio-active chemical, but no detailed information has been published yet.