|Description||An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.|
|Synonyms||(7S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5H)-one; (-)-7-Deacetylcolchicine; NSC 201400;|
Aporphin alkaloid derivative of Isocorydine from plants of the Corydalis genus, Fumariaceae, a long-lasting ganglioblocker, with a sympathetic/parasympathetic a...
Melamine is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity tu...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
Quinoline Alkaloid Extracted from Haplophyllum bucharicum
[Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. , synthetic, originally from Leiurus quinquestriatus hebr...
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.
Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular rel...
Calciseptine is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bon...
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Amaryllidaceae alkaloid from plants of the Amaryllidaceae family. A hypotensive, sedative. Amaryllidaceae alkaloid , from plants of the Amaryllidaceae family.
a nicotinic cholinoreceptor antagonist at the neuromuscular junction; curare-like ganglioblocker. Bis-quaternary quinuclidine derivative, , synthetic.
Aporphine alkaloid , from plants of the Papaveraceae family, a CNS stimulant which enhances the analeptic effects of caffeine and strychnine.
hypotensive, central adrenolytic Semisynthetic derivative of natural alkaloid Galantamine Extracted from Ungernia Victoris (Amarillidaceae Fam.)
Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
Scopolamine, a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity.
A nicotinic antagonist.
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...