N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu - CAS 159439-02-8
Category: Inhibitor
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Molecular Formula:
C32H46N5O17P
Molecular Weight:
803.71
COA:
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Targets:
Src
Description:
N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu is a phosphopeptide ligand for the src SH2 domain with IC50 value of 1 μM. It blocks src interactions with EGFR and FAK.
Synonyms:
N-Acetyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl]-L-α-glutamyl-L-isoleucyl]-L-glutamic acid
MSDS:
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InChIKey:
QQEKQSBIEKQXQS-PSCZMIBCSA-N
InChI:
InChI=1S/C32H46N5O17P/c1-4-16(2)27(31(48)36-22(32(49)50)11-14-26(43)44)37-29(46)21(10-13-25(41)42)34-28(45)20(9-12-24(39)40)35-30(47)23(33-17(3)38)15-18-5-7-19(8-6-18)54-55(51,52)53/h5-8,16,20-23,27H,4,9-15H2,1-3H3,(H,33,38)(H,34,45)(H,35,47)(H,36,48)(H,37,46)(H,39,40)(H,41,42)(H,43,44)(H,49,50)(H2,51,52,53)/t16-,20-,21-,22-,23-,27-/m0/s1
Canonical SMILES:
CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C
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Chemical Structure

CAS 159439-02-8 N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu

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