MTX-211 - CAS 1952236-05-3
Catalog number: B0084-008119
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C20H14Cl2FN5O2S
Molecular Weight:
478.323
COA:
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Targets:
EGFR
Description:
MTX-211 is a dual inhibitor of EGFR and PI3K, which plays important roles in the progression of KRAS mutant colorectal cancer. MTX-211 has the potential for the treatment of KRAS mutant colorectal cancer.
Brife Description:
EGFR/PI3K inhibitor
Purity:
≥98%
Appearance:
Solid powder
Synonyms:
MTX-211; MTX 211; MTX211; CS-7929; CS 7929; CS7929; HY-107364; HY 107364; HY107364; N-(2-chloro-5-(4-((3-chloro-4-fluorophenyl)amino)quinazolin-6-yl)pyridin-3-yl)methanesulfonamide
Solubility:
Soluble in DMSO
MSDS:
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InChIKey:
GUYKCXXNIKKSBC-UHFFFAOYSA-N
InChI:
InChI=1S/C20H14Cl2FN5O2S/c1-31(29,30)28-18-7-12(9-24-19(18)22)11-2-5-17-14(6-11)20(26-10-25-17)27-13-3-4-16(23)15(21)8-13/h2-10,28H,1H3,(H,25,26,27)
Canonical SMILES:
CS(=O)(=O)NC1=C(N=CC(=C1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)Cl
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