|Description||MSPG is a non-selective antagonist of presynaptic mGluRs.|
|Synonyms||(RS)-α-Methyl-4-sulfonophenylglycine; MSPG; (RS)-MSPG; 2-amino-2-(4-sulfophenyl)propanoic acid|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM, is inactive or very weakly antagonizing at other mGlu receptor subtypes.
YM 298198 dihydrochloride
YM 298198 dihydrochloride is a selective mGluR-1 antagonist. In vivo, YM 298198 exhibits an antinociceptive effect in hyperalgesic mice.
DFB is a selective allosteric potentiator of the metabotropic glutamate receptor mGlu5. DFB exhibits no agonistic activity itself, but potentiates (3 - 6-fold) ...
Philanthotoxin 74, also called as PhTx-74, is a synthetic analog of the naturally-occurring wasp venom toxin philanthotoxin-4,3,3. Philanthotoxin 74 is an AMPA ...
Mavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist (IC50=30 nM), as a a selective non-competitive antagonist.
MAP4 is a selective group III metabotropic glutamate receptor (mGluR) antagonist in some electrophysiological systems. It acts as a group II/group III agonist i...
MSPG is a non-selective antagonist of presynaptic mGluRs.
VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displa...