MRT67307 - CAS 1190378-57-4
Catalog number: 1190378-57-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H36N6O2
Molecular Weight:
464.61
COA:
Inquire
Targets:
Salt-inducible Kinases (SIKs) | ULK
Description:
This active molecular is a potent ULK1/2 inhibitor and the IC50 value is 2.9 nM and 1.1 nM. MRT68921 is also a SIK inhibitor.
Purity:
98%
Appearance:
Light yellow to yellow solid
Synonyms:
N-[3-[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide,1190379-70-4 (HCl)
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
UKBGBACORPRCGG-UHFFFAOYSA-N
InChI:
InChI=1S/C26H36N6O2/c33-25(21-5-2-6-21)28-11-3-10-27-24-23(20-8-9-20)17-29-26(31-24)30-22-7-1-4-19(16-22)18-32-12-14-34-15-13-32/h1,4,7,16-17,20-21H,2-3,5-6,8-15,18H2,(H,28,33)(H2,27,29,30,31)
Canonical SMILES:
C1CC(C1)C(=O)NCCCNC2=NC(=NC=C2C3CC3)NC4=CC=CC(=C4)CN5CCOCC5
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Salt-inducible Kinases (SIKs) Products


CAS 1456858-58-4 HG-9-91-01

HG-9-91-01
(CAS: 1456858-58-4)

HG-9-91-01,a small molecule inhibitor that targets specificly salt-inducible kinase (SIKs) IC50: SIK1=0.92 nM; SIK2=6.6 nM; SIK3=9.6 nM

MRT67307 HCl

MRT67307 is a potent and dual IKKϵ and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38...

CAS 1190378-57-4 MRT67307

MRT67307
(CAS: 1190378-57-4)

This active molecular is a potent ULK1/2 inhibitor and the IC50 value is 2.9 nM and 1.1 nM. MRT68921 is also a SIK inhibitor.

SBI-0206965

SBI-0206965 is a highly selective autophagy kinase ULK1 inhibitor with IC50 of 108 nM, about 7-fold selectivity over ULK2.

MRT 67307 dihydrochloride

MRT 67307 is a salt inducible kinase (SIK) inhibitor (IC50 values are 67, 250 and 430 nM for SIK2, SIK1 and SIK3 respectively). MRT67307 potently inhibits ULK1 ...

CAS 1936529-65-5 YKL-05-099

YKL-05-099
(CAS: 1936529-65-5)

YKL-05-099 has slightly less potent SIK2-inhibitory (IC50 = 40 ± 25 nM) and IL-10-enhancing activities (EC50 = 460 ± 110 nM), but is non-toxic at concentrations...

MRT 68921 dihydrochloride

MRT 68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively. It also inhibits autophagy in mouse embryonic fib...

CAS 1190378-57-4 MRT67307

MRT67307
(CAS: 1190378-57-4)

This active molecular is a potent ULK1/2 inhibitor and the IC50 value is 2.9 nM and 1.1 nM. MRT68921 is also a SIK inhibitor.

Chemical Structure

CAS 1190378-57-4 MRT67307

Quick Inquiry

Verification code

Featured Items