|Description||MRT-92 is a potent and selective Smoothened (Smo) receptor inhibitor. MRT-92 displays subnanomolar antagonist activity against Smo in various Hh cell-based assays. MRT-92 inhibits rodent cerebellar granule cell proliferation induced by Hh pathway activation through pharmacologic (half maximal inhibitory concentration [IC50] = 0.4 nM) or genetic manipulation.|
|Synonyms||MRT-92; MRT 92; MRT92|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein. CEF peptides are v-Src-induced cytokines from chicken embryo fib...
TDI-3761 is a novel alphaVbeta3 antagonist developed for osteoporosis therapy. It inhibits alphaVbeta3-dependent cell adhesion without inducing high-affinity li...
Hydrocortisone acetate, a derivative of hydrocortisone, is a corticosteroid compound that has a broad range of anti-inflammatory and immunosuppressive effects a...
AD80, also called as A-196, is a multikinase inhibitor that inhibits against human BRAF, S6K, and SRC and shows strong activity against RET inhibitor.
Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.
3,3,5-Triiodo-L-thyronine(T3), an active metabolite of Thyroxine, could be effective in agonizing both thyroid hormone receptors TRα and TRβ so that might help ...
WWL 123 is an α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50 = 0.43 μM) with antiepileptic activity. It suppresses PTZ-induced seizures in healthy mice and spon...
CDK2, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/...