MP-A08 - CAS 219832-49-2
Catalog number:
219832-49-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H25N3O4S2
Molecular Weight:
519.64
COA:
Inquire
Targets:
SPHK
Description:
MP-A08 is a cell permeable selective inhibitor of sphingosine kinase 2 (Ki=6.9 μM) and 1 (Ki=27 μM) with little affinity for other kinases. In vitro: inhibits cellular S1P production and increases sphingosine and ceramide levels
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Appearance:
Yellow solid
Synonyms:
4-methyl-N-[2-[[2-[(4-methylphenyl)sulfonylamino]phenyl]iminomethyl]phenyl]benzenesulfonamide MP-A08 NSC122314 AC1L9JET Ambcb5562335 SCHEMBL17443540 MCULE-6662772127 N-[2-[[2-(Tosylamino)benzylidene]amino]phenyl]-4-methylbenzenesulfonamide MP A08|NSC 1223
Solubility:
Soluble in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -76℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Boiling Point:
717.1±70.0 °C | Condition: Press: 760 Torr
Density:
1.28±0.1 g/cm3
InChIKey:
FLDBNMYJUMAXDQ-UHFFFAOYSA-N
InChI:
1S/C27H25N3O4S2/c1-20-11-15-23(16-12-20)35(31,32)29-25-8-4-3-7-22(25)19-28-26-9-5-6-10-27(26)30-36(33,34)24-17-13-21(2)14-18-24/h3-19,29-30H,1-2H3
Canonical SMILES:
CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C=NC3=CC=CC=C3NS(=O)(=O)C4=CC=C(C=C4)C
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