|Description||Mosapride, a selective agonist of 5-HT4 receptor, could be used as a astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist.|
|Appearance||White to Off-White Crystalline Solid|
|Solubility||10mM in Ethanol|
|Application||Mosapride is a selective agonist of 5-HT4 receptor and could be used as a astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
|Boiling Point||549.2ºC at 760 mmHg|
The tosylate salt form of Lumateperone which is an highly effective antagonist of 5-HT2A receptor, could be used against insomnia. IC50: 0.54 nM(Ki).
PR-073 is a novel 5-HT7 antagonist, which can inhibit immune responses and treat inflammatory bowel disease (IBD). Preclinical studies demonstrated that PR-073 ...
The (+)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist.
(R)-(+)-8-Methoxy-2-Aminotetraline hydrochloride is a 5-HT1A agonist.
LY 426965 dihydrochloride is a potent and selective 5-HT1A antagonist that is more active than its opposite enantiomer (R)-(-)-LY 426965.
Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo with psychostimulant, anti-ulcer and anti-emetic properties.
Tertatolol, a benzothiopyran derivative, is a potent dual antagonist of beta-adrenoceptor and 5-HT receptor, with antihypertensive effect.
Lofepramine is a serotonin and noradrenalin reuptake inhibitor as an antidepressant.
LP 12 hydrochloride
LP 12 hydrochloride is a 5-HT7 receptor agonist. It can induce relaxation of substance P-induced contractions in guinea pig ileum with EC50 value of 1.77 μM.
MK 212 hydrochloride
MK 212 hydrochloride is a 5-HT2C receptor agonist.
DV 7028 hydrochloride
The hydrochloride salt form of DV 7028, which has been found to be a 5-HT2A receptor antagonist and could restrain collagen-induced serotonin secretion and plat...
Cyproheptadine is a non-selective histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM. It is a first-generation antihistamine with additional a...
Cyclobenzaprine HCl is a muscle relaxant, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the sp...
Pindolol, an Indole derivative, could be used in the treatment of hypertension and arrhythmia for acting as a 5-HT1A/1B receptor antagonist. IC50: 33nM(Ki).
Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) bl...
Org 37684 is a 5-HT2C receptor agonist.
SDZ SER 082 fumarate
SDZ SER 082 fumarate is a selective 5-HT2B/2C receptor antagonist with low affinity for 5-HT1A receptors. SDZ SER 082 fumarate inhibits [3H]-mesulergine binding...
R-96544, the active form of R-102444, is a novel 5-HT receptor antagonist with potent, competitive, and 5-HT(2A)-selective activity (Ki = 1.6 nM). IC50= 2.2, 31...
SB 204070 is a potent and selective 5-HT4 receptor antagonist (pIC50 = 10.1), displaying >5000-fold selectivity over 5-HT1A, 5-HT1D, 5-HT1E, 5-HT2A, 5-HT2C, and...
PU 02 is a potent and selective 5-HT3 receptor antagonist (IC50 values are 0.36 and 0.73 μM in HEK293 cells transfected with human 5-HT3A and 5-HT3AB receptors ...