Moroxydine Hydrochloride - CAS 3160-91-6
Catalog number: 3160-91-6
Category: Inhibitor
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Molecular Formula:
C6H13N5O.HCl
Molecular Weight:
207.66
COA:
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Targets:
Influenza Virus
Description:
Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.
Purity:
>98%
Synonyms:
Moroxydine Hydrochloride; ABOB, Bimolin, Moroxydine free base, SKF 8898-A, SKF 8898A, Virugon, Virumin, Wirumin
MSDS:
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InChIKey:
FXYZDFSNBBOHTA-UHFFFAOYSA-N
InChI:
InChI=1S/C6H13N5O.ClH/c7-5(8)10-6(9)11-1-3-12-4-2-11;/h1-4H2,(H5,7,8,9,10);1H
Canonical SMILES:
C1COCCN1C(=N)N=C(N)N.Cl
1.[Application of derivative spectrophotometric signal multiplier method in multicomponent mixture--determination of moroxydine hydrochloride in Gan Mao Qing capsules].
Lu RG1. Yao Xue Xue Bao. 1992;27(11):871-4.
This paper provides a basic principle and experimental technique of derivative signal multiplier spectrophotometry in multicomponent mixture. A microcomputer was used to process the spectral data measured on a manual spectrophotometer (UV-7520) for the determination of moroxydine hydrochloride in Gan Mao Qing capsules. Quantitative analysis of multicomponent mixture can be done without sample separation. The selection of optimal wavelength pairs is performed through the program with a computer. The method needs no special spectrophotometer and is simple, rapid and easy to operate. The mean recovery was 99.98 +/- 0.53% (n = 12).
2.[Detection of type 1 and 2 herpetic antigens by immunofluorescence in patients with chronic or recurrent keratoconjunctivitis receiving therapy based on etiology].
Athanasiu P, Anghelescu S, Deltin L, Pop D Popa D, Dumitrescu AM, Macarie I, Mihail V. Virologie. 1986 Oct-Dec;37(4):247-52.
Immunofluorescence (IF) techniques were used to evaluate the therapeutical efficiency of moroxidine hydrochloride against herpes virus (HSV) induced keratoconjunctivitis. In 56 out of the 77 followed-up and treated patients, the IF reactions revealed the presence of both types 1 and 2 of herpes virus, while in 21 only type 1 was found. The treatment with moroxidine hydrochloride led to a reduction of 63% and 92%, respectively, of the incidence of herpes virus type 1 and 2 antigens in the conjunctival cells, coincident with the improvement of clinical symptoms or persistent recovery.
3.[Separation of bases, phenols and pharmaceuticals on ionic liquid-modified silica stationary phase with pure water as mobile phase].
Wang X1, Qiu H, Liu X, Jiang S. Se Pu. 2011 Mar;29(3):269-72.
N-methylimidazolium ionic liquid (IL) -modified silica was prepared with the reaction of 3-chloropropyl modified silica and N-methylimidazole using toluene as solvent. Based on the multiple interactions between N-methylimidazolium IL-modified silica and analytes such as hydrophobic interaction, electrostatic attraction, repulsion interaction, hydrogen-bonding, etc., the bases (cytosine, thymine, 2-aminopyrimidine and 6-chloroguanine), phenols (m-aminophenol, resorcinol and m-nitrophenol) and three pharmaceuticals (moroxydine hydrochloride, acyclovir and cephalexin hydrate) were separated successfully with only pure water as the mobile phase. These chromatographic separations are environmental friendly, economical and convenient, without any organic solvent or buffer additive. The retention mechanism of these samples on the stationary phase was also investigated.
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CAS 3160-91-6 Moroxydine Hydrochloride

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