Moexipril HCl - CAS 82586-52-5
Catalog number:
82586-52-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H35ClN2O7
Molecular Weight:
535.03
COA:
Inquire
Targets:
Angiotensin-converting Enzyme (ACE)
Description:
Moexipril HCl is a potent orally active non-sulfhydryl angiotensin converting enzyme inhibitor (ACE) with IC50 of 0.041 μM, which is used for the treatment of hypertension and congestive heart failure.
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Purity:
>98%
Synonyms:
CI-906, PD-109452-2
MSDS:
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1.Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceu
el-Hay SS1, Colyer CL, Hassan WS, Shalaby A. J Fluoresc. 2012 Jan;22(1):247-52. doi: 10.1007/s10895-011-0954-8. Epub 2011 Aug 19.
A simple, selective and sensitive luminescence method has been developed for the assay of etodolac (I), moxepril HCl (II) and fexofenadine HCl (III) in bulk drug and pharmaceutical formulations. The method is based on the luminescence sensitization of europium (Eu(3+)) by complexation with the studied drugs. The fluorescence intensities of the products were measured at 667 nm for (I) and at 615 for (II) and (III) while exciting at 276 for all the studied drugs. The fluorescence intensity was directly proportional to the concentration over the range (20-280), (40-240) and (30-80) ng/ml with limits of detection (LOD) = 0.93, 0.92 and 0.95 μg/ml for drugs I, II and III respectively. Optimum conditions for the formation of the complex in methanol were carefully studied. The proposed method was successfully applied for the assay of the studied drugs in pharmaceutical formulations with excellent recovery.
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CAS 82586-52-5 Moexipril HCl

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