MN-64 - CAS 92831-11-3
Catalog number: 92831-11-3
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H16O2
Molecular Weight:
264.32
COA:
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Targets:
Tankyrase-1
Description:
MN-64 is a very potent and selective inhibitor of Tankyrase 1 and 2 with IC50 values of 6 and 72 nM, respectively. It blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter system. It affects cell proliferation with potential treatment for cancers. It is a flavonoid compound with anti-cancer/ anti-bacterial properties. It was effective Wnt/β- catenin inhibitors at 1 μM, and inhibited STF luciferase activity at 200 nM in the HEK293 cells in vitro.
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
2-(4-Isopropylpheny)-4H-chroMen-4-one;2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one;MN64;2-(4-propan-2-ylphenyl)chromen-4-one
Solubility:
10 mM in DMSO
Storage:
2-8ºC
MSDS:
Inquire
Application:
MN-64 has anti-cancer/ anti-bacterial properties and is used for the treatment for cancers.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Grams to Kilograms
Boiling Point:
389.8±42.0 °C | Condition: Press: 760 Torr
Melting Point:
63-64 °C | Condition: Solv: ethanol (64-17-5)
Density:
1.152±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
PYTOHIUBXSJKQH-UHFFFAOYSA-N
InChI:
InChI=1S/C18H16O2/c1-12(2)13-7-9-14(10-8-13)18-11-16(19)15-5-3-4-6-17(15)20-18/h3-12H,1-2H3
Canonical SMILES:
CC(C)C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2
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MN-64
(CAS: 92831-11-3)

MN-64 is a very potent and selective inhibitor of Tankyrase 1 and 2 with IC50 values of 6 and 72 nM, respectively. It blocks Wnt signaling in HEK293 cells conta...

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