MMV390048 - CAS 1314883-11-8
Catalog number:
1314883-11-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H14F3N3O2S
Molecular Weight:
393.38
COA:
Inquire
Targets:
Others
Description:
MMV390048 is a novel antimalarial compound and it can competitively inhibit the binding of only a single protein, P. falciparum PI4 kinase, to the beads. MV390048 can become a child-friendly drug candidate for uncomplicated malaria that could be given as one single dose, completing the treatment in just one day. In May 2016, Phase I/II clinical trials in Malaria (In volunteers) in Australia was on-going.
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Purity:
98%
Appearance:
Powder
Synonyms:
UNII-0Z5T00JJ10;5-(4-(methylsulfonyl)phenyl)-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine;MMV390048; MMV-390048; MMV 390048; MMV-048; MMV 048; MMV048.
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Malaria
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
RTJQABCNNLMCJF-UHFFFAOYSA-N
InChI:
1S/C18H14F3N3O2S/c1-27(25,26)14-5-2-11(3-6-14)13-8-15(17(22)24-10-13)12-4-7-16(23-9-12)18(19,20)21/h2-10H,1H3,(H2,22,24)
Canonical SMILES:
CS(=O)(=O)c1ccc(cc1)c2cnc(N)c(c2)c3ccc(nc3)C(F)(F)F
Current Developer:
Medicines for Malaria Venture; Technology Innovation Agency; University of Cape Town
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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