MMAD hydrochloride - CAS 173441-26-4
Catalog number:
173441-26-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C41H67ClN6O6S
Molecular Weight:
807.53
COA:
Inquire
Targets:
ADCs Cytotoxin
Description:
For comparison purposes, the ADC A1 -mc-MMAD and/or A1 -vc-MMAD were used. The linker payload, mc-MMAD (6-maleimidocaproyl-monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule. The linker payload mc- Val-Cit-PABA-MMAD or vc-MMAD (maleimidocapronic -valine-citruline-p- aminobenzyloxycarbonyl- monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule.
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Purity:
>98%
Synonyms:
Demethyldolastatin 10 hydrochloride; Monomethylauristatin D hydrochloride; Monomethyl Dolastatin 10 hydrochloride
MSDS:
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CAS 173441-26-4 MMAD hydrochloride

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