|Description||ML385 is a novel and specific inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2; IC50 = 1.9 µM), and blocks NRF2 transcriptional activity, and enhances the efficacy of carboplatin and other chemotherapeutic drugs in lung cancer cells (NSCLC).|
|Brife Description||A potent and selective NRF2 inhibitor (Nrf2; IC50 = 1.9 µM)|
|Synonyms||2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide; ML-385; ML 385|
|Solubility||DMSO: ≥ 30 mg/mL|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
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