ML348 - CAS 899713-86-1
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H17ClF3N3O3
Molecular Weight:
415.79
COA:
Inquire
Targets:
Phospholipase
Description:
ML348, also known as CID 3238952 or SID 160654487, is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). It is 14-fold selective for LYPLA1 over LYPLA2 (IC50 = >3,000) and demonstrates little activity against a panel of more than 20 other serine hydrolases (IC50s = >10,000)
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Appearance:
Solid powder
Synonyms:
N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide; ML348; ML-348; ML 348; CID 3238952; SID 160654487.
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
546.2±50.0 °C at 760 Torr
Density:
1.422±0.06 g/cm3
InChIKey:
OXKNHBBDOIMFFQ-UHFFFAOYSA-N
InChI:
1S/C18H17ClF3N3O3/c19-13-4-3-12(18(20,21)22)10-14(13)23-16(26)11-24-5-7-25(8-6-24)17(27)15-2-1-9-28-15/h1-4,9-10H,5-8,11H2,(H,23,26)
Canonical SMILES:
O=C(NC1=CC(C(F)(F)F)=CC=C1Cl)CN2CCN(C(C3=CC=CO3)=O)CC2
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Chemical Structure

CAS 899713-86-1 ML348

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