|Description||ML337 is a Selective negative allosteric modulator of mGlu3 with IC50 value of 593 nM. It shows no activity at mGlu1, mGlu2 or mGlu4-8 at concentrations up to 30 μM. ML337 is a best-in-class probe for studying non-competitive antagonism of mGlu3.|
|Synonyms||CHEMBL2385886; ML337; ML 337; ML-337; MLS004580699; GTPL8765;(R)-(2-fluoro-4-((4-methoxyphenyl)ethynyl)phenyl)(3-hydroxypiperidin-1-yl)methanone|
|Solubility||DMSO to 100 mM ethanol to 20 mM|
|Application||in vitro and in vivo probe for studying non-competitive antagonism of mGlu3|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
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