|Description||ML311, also known as EU-5346, is a potent and selective inhibitor of the Protein-Protein Interaction of Mcl-1 and Bim. EU-5346 inhibits proliferation of Her2-positive BC cells in a dose-dependent manner. ML311 is a useful tool for studying lymphoid tumorigenesis and to demonstrate the potential for using this strategy in therapies intended to bypass apoptosis resistance pathways that are activated in drug-resistant tumors.|
|Synonyms||7-[(4-Ethylpiperazin-1-yl)-[4-(trifluoromethyl)phenyl]methyl]quinolin-8-ol; ML311; ML-311; ML 311; EU-5346; EU 5346; EU5346.|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||515.7±45.0 °C at 760 Torr|
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