ML241 - CAS 1346528-06-0
Catalog number: 1346528-06-0
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H24N4O
Molecular Weight:
372.46
COA:
Inquire
Targets:
ATPase/GTPase
Description:
ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the treatment of cancer.
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Purity:
98%
Related CAS:
2070015-13-1 (HCl)
Appearance:
Solid powder
Synonyms:
2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine; ML241; ML-241; ML 241
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
anticancer
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Gram
InChIKey:
RMZPVQQGYVSLAP-UHFFFAOYSA-N
InChI:
1S/C23H24N4O/c1-2-8-17(9-3-1)16-24-22-18-10-4-5-11-19(18)25-23(26-22)27-14-15-28-21-13-7-6-12-20(21)27/h1-3,6-9,12-13H,4-5,10-11,14-16H2,(H,24,25,26)
Canonical SMILES:
C1(N2CCOC3=CC=CC=C23)=NC(NCC4=CC=CC=C4)=C5CCCCC5=N1
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