MK-8245 Trifluoroacetate - CAS 1415559-41-9
Catalog number: 1415559-41-9
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C19H17BrF4N6O6
Molecular Weight:
581.28
COA:
Inquire
Targets:
Stearoyl-CoA Desaturase (SCD)
Description:
MK-8245 Trifluoroacetate, a phenoxy piperidine isoxazole derivative, is a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor that has the potential for treatment of dyslipidemia and diabetes. IC50: human SCD1= 1 nM; rat SCD1 and mouse SCD1= 3 nM
Appearance:
Light yellow to yellow(solid)
Synonyms:
MK-8245 Trifluoroacetate; MK 8245 Trifluoroacetate; MK8245 Trifluoroacetate; 2-[5-[3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2-oxazol-5-yl]tetrazol-2-yl]acetic acid;2,2,2-trifluoroacetic acid; MK-8245 (Trifluoroacetate); 1415559-41-9; 2,2,2-Trifluoroacetic acid compound with 2-(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-Yl
Solubility:
Soluble to 10 mM in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -22℃ for long term (months to years).
MSDS:
Inquire
Application:
Antidiabetic; Antidyslipidemic
Shelf Life:
2 years
Quantity:
Grams-Kilos
InChIKey:
LEBPCMXFQYATAK-UHFFFAOYSA-N
InChI:
1S/C17H16BrFN6O4.C2HF3O2/c18-12-2-1-10(19)7-13(12)28-11-3-5-24(6-4-11)15-8-14(29-22-15)17-20-23-25(21-17)9-16(26)27;3-2(4,5)1(6)7/h1-2,7-8,11H,3-6,9H2,(H,26,27);(H,6,7)
Canonical SMILES:
C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O.C(=O)(C(F)(F)F)O
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