|Targets||Stearoyl-CoA Desaturase (SCD)|
|Description||MK-8245 is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.|
|Related CAS||1415559-41-9 (TFA)|
|Synonyms||4-(2-Bromo-5-fluorophenoxy)-1-[5-(2H-tetrazol-5-yl)-3-isoxazolyl]piperidine; MK-8245; MK8245; MK8245|
MK-8245 is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-di...
MK-8245 Trifluoroacetate, a phenoxy piperidine isoxazole derivative, is a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor that has the potential for trea...
A939572 is a effective and highly selective cell-permeable inhibitor of SCD1(stearoyl-CoA desaturase 1) which could be mediated by hormonal and dietary actions....