MK-7246 - CAS 1218918-62-7
Catalog number:
1218918-62-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H21FN2O4S
Molecular Weight:
416.47
COA:
Inquire
Targets:
CRTH2 (GPR44)
Description:
This active molecular is a selective chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) antagonist and is used for the treatment of respiratory tract disorders originated by Merck & Co. CRTH2 is a G protein-coupled receptor that has been reported to modulate inflammatory responses in animal models of asthma, allergic rhinitis and atopic dermatitis. No recent reports of development identified for phase-I development in Respiratory-tract-disorders in USA were published yet.
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Purity:
98%
Appearance:
Powder
Synonyms:
(7R)-7-[[(4-Fluorophenyl)sulfonyl]methylamino]-6,7,8,9-tetrahydro-pyrido[1,2-a]indole-10-acetic Acid
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Respiratory tract disorders
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
JTCAGRAKUAAYDY-OAHLLOKOSA-N
InChI:
InChI=1S/C21H21FN2O4S/c1-23(29(27,28)16-9-6-14(22)7-10-16)15-8-11-20-18(12-21(25)26)17-4-2-3-5-19(17)24(20)13-15/h2-7,9-10,15H,8,11-13H2,1H3,(H,25,26)/t15-/m1/s1
Canonical SMILES:
CN(C1CCC2=C(C3=CC=CC=C3N2C1)CC(=O)O)S(=O)(=O)C4=CC=C(C=C4)F
Current Developer:
Originator: Merck & Co
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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