|Description||MK-4827 HCl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. It has a great activity in cancer cells with mutant BRCA-1 and BRCA-2, >330-fold selective against PARP3, V-PARP and Tank1.|
|Related CAS||1613220-15-7 (tosylate hydrate)|
|Appearance||Light yellow solid powder|
|Synonyms||(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride; MK4827; MK 4827; MK4827; Niraparib; Niraparib HCl; Niraparib hydrochloride|
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