MK 287 - CAS 135947-75-0
Catalog number:
135947-75-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H34O9S
Molecular Weight:
510.60
COA:
Inquire
Targets:
Platelet-activating factor receptor (PAF-R)
Description:
MK-287 is platelet activating factor (PAF) inhibitor originated by Merck & Co. It can potently inhibit [3H]C18-PAF binding to human platelet, PMN (polymorphonuclear leukocyte) and lung membranes. The inhibitory effects are competitive and stereospecific. Clinical trials for asthma was discontinued.
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Purity:
98%
Appearance:
Powder
Synonyms:
L-680573;2-((3-methoxy-2-propoxy-5-((2S,5S)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran-2-yl)phenyl)sulfonyl)ethan-1-ol
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Asthma
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
WXIDMVGKJBAEFP-OALUTQOASA-N
InChI:
1S/C25H34O9S/c1-6-10-33-25-22(31-4)14-17(15-23(25)35(27,28)11-9-26)19-8-7-18(34-19)16-12-20(29-2)24(32-5)21(13-16)30-3/h12-15,18-19,26H,6-11H2,1-5H3/t18-,19-/m0/s1
Canonical SMILES:
C(CS(=O)(=O)c1c(c(cc(c1)[C@H]1O[C@@H](CC1)c1cc(c(c(c1)OC)OC)OC)OC)OCCC)O
Current Developer:
Originator Merck & Co
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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