MK-0668 mesylate - CAS 865111-04-2
Catalog number:
865111-04-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C31-H30-Cl2-N6-O6-S.C-H4-O3-S
Molecular Weight:
781.69
COA:
Inquire
Targets:
CTLA4
Description:
MK-0668 is an antagonist of very late antigen-4 with picomolar, whole blood activity and slow dissociation rates were discovered by incorporating an amino substituent on the proline fragment of the initial lead structure.
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Purity:
98%
Appearance:
Powder
Synonyms:
(S)-2-((2S,4R)-1-((3-cyanophenyl)sulfonyl)-4-(cyclobutylamino)pyrrolidine-2-carboxamido)-3-(4-(3,5-dichloroisonicotinamido)phenyl)propanoic acid mesylate
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
KHZPBUGRFNTMOR-YHEIIOCHSA-N
InChI:
1S/C31H30Cl2N6O6S.CH4O3S/c32-24-15-35-16-25(33)28(24)30(41)37-21-9-7-18(8-10-21)12-26(31(42)43)38-29(40)27-13-22(36-20-4-2-5-20)17-39(27)46(44,45)23-6-1-3-19(11-23)14-34;1-5(2,3)4/h1,3,6-11,15-16,20,22,26-27,36H,2,4-5,12-13,17H2,(H,37,41)(H,38,40)(H,42,43);1H3,(H,2,3,4)/t22-,26+,27+;/m1./s1
Canonical SMILES:
CS(=O)(=O)O.c1cc(cc(c1)S(=O)(=O)N2C[C@@H](C[C@H]2C(=O)N[C@@H](Cc3ccc(cc3)NC(=O)c4c(cncc4Cl)Cl)C(=O)O)NC5CCC5)C#N
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