|Description||MK-0634, also called as L-796568, is an β3 adrenergic receptor agonist that was progressed into clinical studies for the treatment of obesity in the early 2000s but discontinued due to unacceptable toxicity.|
|Synonyms||N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]benzenesulfonamide;dihydrochloride; L-796568 dihydrochloride; 211031-81-1 (L-796568 dihydrochloride); 211031-01-5 (L-796568 Free base)|
Propranolol hydrochloride, with antihypertensive, antianginal and antiarrhythmic (class II) properties, is a non-cardioselective adrenergic-beta antagonist and ...
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Penbutolol is a sympathomimetic drug used to treat mild to moderate high blood pressure by binding to both beta-1 adrenergic receptors and beta-2 adrenergic rec...
Asenapine hydrochloride, also called Org 5222 and HSDB 8061, shows high affinity for numerous receptors including 5-HT receptor and adrenergic receptor. (pKi: 5...
Hydrocortisone-17-butyrate, a glucocorticoid compound, could be used as antiinflammatory and immunosuppresive agent.
ICI141292, also known as Epanolol, is a adrenergic β-antagonist with a greater affinity for β1- than β2-adrenoceptors, which is used for treatment of hypertensi...
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MK-0634, also called as L-796568, is an β3 adrenergic receptor agonist that was progressed into clinical studies for the treatment of obesity in the early 2000s...
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Nifenalol, also known as INPEA, is a novel antagonist of β-adrenoceptors.
Nolomirole is a Alpha 2 adrenergic receptor and Dopamine D2 receptor agonist. Nolomirole can attenuate the heart failure signs in the monocrotaline-induced cong...
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ABT-866 is a novel alpha-adrenoceptor agent that demonstrates intrinsic activity at the α1A-adrenoceptor subtype present in the rabbit urethra (pD2=6.22, with 8...
Milveterol is a long-acting β(2)-adrenoceptor agonist under the development of GlaxoSmithKline. Phase II trials for the treatment of Chronic obstructive pulmona...
Tedatioxetine is an antidepressant agent. It acts as a triple reuptake inhibitor and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. It was discov...