|Description||Mitotane, is an antineoplastic medication used in the treatment of adrenocortical carcinoma.|
PD 130908 is an effective hypoxic cytotoxin as an analogue of RSU 1069, but less potent than the hypoxic cell radiosensitizer RSU 1069. Toxicity toward hypoxic ...
WWL70 is a potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM). ABHD6 is a serine hydrolase that is highly expressed in mammalian brain.
Metixene is an anticholinergic used as an antiparkinsonian agent for the symptomatic treatment of parkinsonism.
Hydralazine HCl is a hydrochloride salt of hydralazine (Apresoline) that is a direct-acting smooth muscle relaxant with an IC50 of 1.9 mM.
Hydroxyamphetamine, an active metabolite product of amphetamine, is a prescription drug that could stimulate the sympathetic nervous system and commonly be used...
CVT-12012 is a bio-active chemical compound and is highly potent in a human cell-based (HEPG2) SCD assay with IC50 value of 6nM.
AT-308 is a synthetic bio-active chemical as an oral hypoglycaemic agent.
Kinetin is a type of cytokinin, a class of plant hormone that promotes cell division.
Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)
AZD0156 is an orally active, potent and selective ataxia telangiectasia mutated (ATM) kinase inhibitor, used for cancer treatment. AZD0156 prevents DNA damage c...
Sograzepide, a benzodiazepin derivative, has been found to be a gastric receptor as well as CCK2 receptor antagonist that could be useful against chronic atroph...
Olesoxime (TRO19622) is an experimental neuroprotective drug. It is the lead compound of Trophos' cholesterol-oxime compound family of mitochondrial pore modula...
The hydrochloride salt form of Droxicainide, a piperidine derivative, has been found to be an potential antiarrhythmic agent.
Azeliragon is a potent and orally active RAGE inhibitor as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD).
Mice treated with vehicle showed significantly enlarged tumors, whereas mice treated with YL-109 showed attenuated tumor growth using MCF-7 cells. Interestingly...
GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity.
Benzydamine hydrochlorid is structurally unrelated to the corticosteroids. The action of benzydamine may be mediated by the prostaglandin system.
BMS 433771 is a potent inhibitor of RSV replication in vitro with an average EC of 20nM
N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast.
Cortisone is a synthetic steroid hormone which are widely used for the treatment of inﬂammation; a corticosterone analog that has approximately twice the anti-i...