Minalrestat - CAS 129688-50-2
Catalog number: 129688-50-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C19H11BrF2N2O4
Molecular Weight:
449.21
COA:
Inquire
Targets:
Aldehyde Reductase
Description:
Minalrestat is an aldose reductase inhibitor originated by Wyeth. In Aug 2002, Phase-III for Diabetic retinopathy was discontinued in USA and Europe.
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Purity:
98%
Appearance:
Powder
Synonyms:
WAY-ARI-509; Minalrestat [USAN:INN];2-[(4-bromo-2-fluorophenyl)methyl]-6-fluorospiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'-tetrone
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Diabetic retinopathy
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
BMHZAHGTGIZZCT-UHFFFAOYSA-N
InChI:
InChI=1S/C19H11BrF2N2O4/c20-10-2-1-9(14(22)5-10)8-24-16(26)12-4-3-11(21)6-13(12)19(18(24)28)7-15(25)23-17(19)27/h1-6H,7-8H2,(H,23,25,27)
Canonical SMILES:
C1C(=O)NC(=O)C12C3=C(C=CC(=C3)F)C(=O)N(C2=O)CC4=C(C=C(C=C4)Br)F
Current Developer:
Originator:Wyeth
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CAS 129688-50-2 Minalrestat

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