|Description||Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries. It inhibits the reuptake of serotonin and norepinephrine in an approximately 1:3 ratio. It is well absorbed after oral dosing and has a bioavailability of 85%. It is conjugated to the inactive glucuronide and excreted in the urine as unchanged drug and conjugate. Only traces of active metabolites are found.|
|Synonyms||Dalcipran; Ixel; Savella; Toledomin|
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