|Targets||Glucosylceramide Synthase | α- and β-glucosidases|
|Description||Miglustat HCl is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). It also inhibits glucosidase I and II, as well as HIV-1 and HIV-2 infection of peripheral blood mononuclear cells (PBMCs).|
|B0084-101894||10 mg||$398||In stock|
|B0084-101894||1 g||$3980||In stock|
|Related CAS||72599-27-0 (free base)|
|Appearance||White to Off-white Solid|
|Synonyms||Miglustat hydrochloride; Miglustat (hydrochloride); N-Butyldeoxynojirimycin, Hydrochloride; N-Butyl-DNJ, HCl; NB-DNJ, HCl|
Castanospermine is an inhibitor of all forms of α- and β-glucosidases, especially glucosidase l. It inhibits lysosomal and neutral α-glucosidases with Ki values...
Ibiglustat is a selective Glucosylceramide synthase inhibitor. It can block the formation of glucosylceramide (GL-1) which is a key intermediate in the synthesi...
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancrea...
Eliglustat hemitartrate is a specific inhibitor of glucosylceramide synthase. It is under development as an oral substrate reduction therapy for Gaucher disease...
1-Deoxynojirimycin, also called Duvoglustat, is produced by Bacillus species. It is a glucose analog that can inhibit α-glucosidase I and II. 1-Deoxynojirimycin...