|Description||Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used at a concentration of 0.5 nM.2 The PP1 IC50 is about 1.7 nM. Microcystins are at least 10 times more potent as serine/threonine PP inhibitors than okadaic acid, another microalgal toxin also used for this purpose.|
Napelline is a diterpenoid alkaloid from plants of the Aconitum,genus, a potent antiarrhythmic with weak hypotensive and N-cholinoblocking effects.
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...
an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
A non-toxic, complement-activating component of cobra venom Three polypeptide chains with molecular masses of about 70, 50, and 30 kDa, the two large subunits b...
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Etbicuphat is a GABAa receptor antagonist known to cause convulsions, seizures and other neuromuscular related episodes. Used in the study of anti-epileptic dru...
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...
Hydrobromide salt of (+)-Lappaconitine, a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
Ryanodine High Purity
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
Extracted from Haplophyllum perforatum plant (Rutaceae fam.). An antiarrhythmic of first class Quinoline alkaloid
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
Deltaline has a lycoctonine carbon-atom skeleton with four six-membered rings and three five-membered rings among; three of the six-membered rings adopt chair c...
Lqh alpha IT Recombinant
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Hyoscyamine is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, non-selective antagonist at Muscarinic recepto...
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
Seco-Duocarmycin DMA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants includ...