|Description||Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs).|
CCG 203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM). CCG 203971 inhibits fibrosis by targeting the MRTF/SRF gene ...
MDL 72527 is a polyamine oxidase inhibitor. It can block the production of H2O2 and increase the cells survival. MDL 72527 shows anticancer and neuroprotective ...
T7 Tag Peptide, an epitope tag composed of an 11-residue peptide encoded from the leader sequence of the T7 bacteriophage gene10, and serves as a tag in many ex...
A 357300 hydrochloride
A 357300 hydrochloride is a potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2). In murine models, it significantly inhibits CHP-134-derive...
EC330 is a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range, blocked formation ...
Ginsenoside Re, extracted from the traditional Chinese herb ginseng, responsible for some of the pharmacological functions.
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, ...
Fosbretabulin, also called as CA4P, has antitumor activity against anaplastic thyroid cancer (ATC) cell lines. Fosbretabulin, a novel water-soluble vascular-dis...
Sodium Molybdate, anhydrous
Sodium molybdate is used as source of molybdate and it is often used in the form of Sodium molybdate dihydrate. It inactivated both the active and inactive form...
A metabolite of Gleevec, a tyrosine kinase inhibitor.
Vernakalant is an drug under regulatory for the treatment for conversion of atrial fibrillation. It blocks atrial potassium channels, thereby prolonging repolar...
Stauprimide is an enhancer stem cell differentiation into endoderm. In vitro differentiation of embryonic stem cells is of great interest to regenerative medici...
D-Glucosamine hydrochloride is present in mucopolysaccharides and in polysaccharides found in bacteria, fungi, higher plants has been used as a standard to quan...
Rbin-2 (ribozinoindole-2) is a potent and reversible inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular acti...
Dehydrocorydaline, an alkaloid derived from the tubers of Corydalis ambigua, with potential anti-tumor activity it significantly inhibits MCF-7 cell proliferati...
LY 243670 is a bio-active molecular, but detailed information were not published yet.
Metyrapol, a dipyridine derivative, has been found to be a 11-deoxycorticosterone hydroxylation inhibitor and could always used as a medical diagnostic reagent ...
Ac9-25 is a N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting...
Carotegrast is an anti-inflammatory agent as a Integrin alpha4 inhibitor.