MHY 908 - CAS 1393371-39-5
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C17H14ClNO3S
Molecular Weight:
347.82
COA:
Inquire
Targets:
PPAR
Description:
MHY 908 is a dual PPARα/γ agonist and a melanogenesis inhibitor that suppresses mushroom tyrosinase activity (IC50 value 8.19 μM). MHY908 exhibits more potent activation of PPARα and PPARγ than fenofibrate and rosiglitazone, and enhances the binding and transcriptional activity of PPARα and -γ in AC2F cells. It reduces serum glucose, triglyceride, and insulin levels, however increases adiponectin levels without body weight gain.
Brife Description:
PPARα/γ agonist, melanogenesis inhibitor
Purity:
99%
Synonyms:
2-[4-(5-Chloro-2-benzothiazolyl)phenoxy]-2-methylpropanoic acid
MSDS:
Inquire
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related PPAR Products


CAS 50892-23-4 Pirinixic Acid

Pirinixic Acid
(CAS: 50892-23-4)

WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with EC50 of 1.5 μM.

CAS 223132-37-4 Inolitazone

Inolitazone
(CAS: 223132-37-4)

Inolitazone is an orally bioavailable PAPR-gamma inhibitor with potential antineoplastic activity. Inolitazone binds to and activates peroxisome proliferation-a...

CAS 97322-87-7 Troglitazone

Troglitazone
(CAS: 97322-87-7)

Troglitazone, PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity, which was approved for the treatment of...

CAS 824932-88-9 GFT505

GFT505
(CAS: 824932-88-9)

Elafibranor is an agonist of the peroxisome proliferator-activated receptor-α and peroxisome proliferator-activated receptor-δ. It induces resolution of nonalco...

CAS 317318-70-0 GW501516

GW501516
(CAS: 317318-70-0)

GW501516 is a potent and highly selective PPARβ/δ agonist, with EC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ. Phase 4.

CAS 52214-84-3 Ciprofibrate

Ciprofibrate
(CAS: 52214-84-3)

Ciprofibrate is a peroxisome proliferator-activated receptor agonist.

CAS 1014691-61-2 GSK0660

GSK0660
(CAS: 1014691-61-2)

GSK0660 is a selective PPARδ antagonist. GSK0660 blocks the effect of TNFα on the expressions of cytokines involved in leukocyte recruitment, including CCL8, CC...

CAS 622402-22-6 GW-590735

GW-590735
(CAS: 622402-22-6)

GW-590735 is a potent and selective agonist of PPARα. Its EC50 value is 4 nM for the expression a GAL4-responsive reporter gene and at least 500-fold selectivit...

CAS 1453-93-6 PROTOPANAXATRIOL

PROTOPANAXATRIOL
(CAS: 1453-93-6)

Protopanaxatriol is a dammarane-type tetracyclic triterpene sapogenins found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng). It may have a ...

CAS 317318-84-6 GW0742

GW0742
(CAS: 317318-84-6)

GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ.

CAS 851528-79-5 Seladelpar

Seladelpar
(CAS: 851528-79-5)

Seladelpar is a selective peroxisome proliferator-activated receptor -δ receptor agonist. Phase II clinical trials for the treatment of Hyperlipidaemia, Hyperli...

CAS 251565-85-2 Tesaglitazar

Tesaglitazar
(CAS: 251565-85-2)

Tesaglitazar is a dual-acting agonist of PPARα/γ (IC50 = 0.35 and 3.8 μM for PPARγ and PPARα, respectively). It reduces insulin resistance in obese Zucker rats ...

CAS 223132-38-5 Inolitazone dihydrochloride

Inolitazone dihydrochloride
(CAS: 223132-38-5)

In vitro, the IC50 for growth inhibition is approximately 0.8 nM while anaplastic thyroid carcinoma (ATC) tumor growth was inhibited three- to fourfold in nude ...

INT 131
(CAS: 315224-26-1)

INT 131 is a hypoglycemic agent, displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared...

CAS 331741-94-7 Muraglitazar

Muraglitazar
(CAS: 331741-94-7)

Muraglitazar is a peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist(EC50s = 320 and 110 nM in vitro).

CAS 425671-29-0 LY-518674

LY-518674
(CAS: 425671-29-0)

LY518674, a phenoxypropionic acid derivative, is a Potent and selective PPAR-alpha agonist produced a dose-dependent increase in serum HDL-c, resulting in 208 +...

Saroglitazar
(CAS: 495399-09-2)

Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity as a drug for the treatment...

CAS 927961-18-0 Lanifibranor

Lanifibranor
(CAS: 927961-18-0)

Lanifibranor is a peroxisome proliferator-activated receptors (PPAR) agonist.

CAS 213411-84-8 BM152054

BM152054
(CAS: 213411-84-8)

BM152054, a thiazolidinedione, revealed to be potent PPARg-activators in transient transfection assays in vitro.

CAS 539813-69-9 PPAR agonist 1

PPAR agonist 1
(CAS: 539813-69-9)

An agonist of PPAR α and PPAR γ

Chemical Structure

CAS 1393371-39-5 MHY 908

Quick Inquiry

Verification code

Featured Items