|Description||MHY 908 is a dual PPARα/γ agonist and a melanogenesis inhibitor that suppresses mushroom tyrosinase activity (IC50 value 8.19 μM). MHY908 exhibits more potent activation of PPARα and PPARγ than fenofibrate and rosiglitazone, and enhances the binding and transcriptional activity of PPARα and -γ in AC2F cells. It reduces serum glucose, triglyceride, and insulin levels, however increases adiponectin levels without body weight gain.|
|Brife Description||PPARα/γ agonist, melanogenesis inhibitor|
|Synonyms||MHY908; MHY 908; MHY-908; 2-[4-(5-Chloro-2-benzothiazolyl)phenoxy]-2-methylpropanoic acid|
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