MGAT2-IN-1 - CAS 1800025-30-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H21ClF5N7O3S
Molecular Weight:
654.01
COA:
Inquire
Targets:
Others
Description:
An orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) (IC50= 7.8 for human, and 2.4 nM for mouse MGAT2).
Publictions citing BOC Sciences Products
  • >> More
Synonyms:
N-(4-chloro-2,6-difluorophenyl)-1-[5-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]pyrimidin-2-yl]-7-(2-oxopyrrolidin-1-yl)-2,3-dihydroindole-5-sulfonamide
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
838.7±75.0 ℃ at 760 Torr
Density:
1.66±0.1 g/cm3
InChIKey:
VSZRYLHBOKTNBO-UHFFFAOYSA-N
InChI:
1S/C27H21ClF5N7O3S/c1-38-20(11-22(36-38)27(31,32)33)15-12-34-26(35-13-15)40-6-4-14-7-17(10-21(25(14)40)39-5-2-3-23(39)41)44(42,43)37-24-18(29)8-16(28)9-19(24)30/h7-13,37H,2-6H2,1H3
Canonical SMILES:
CN1C(=CC(=N1)C(F)(F)F)C2=CN=C(N=C2)N3CCC4=CC(=CC(=C43)N5CCCC5=O)S(=O)(=O)NC6=C(C=C(C=C6F)Cl)F
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 136-40-3 Phenazopyridine Hydrochloride

Phenazopyridine Hydrochloride
(CAS: 136-40-3)

Phenazopyridine Hydrochloride is a local analgesic that has been used in urinary tract disorders.

CAS 144092-28-4 Xenin

Xenin
(CAS: 144092-28-4)

Xenin, a 25-amino acid peptide initially isolated from human gastric mucosa, has 6 C-terminal amino acids in common with amphibian xenopsin. Xenin may stimulate...

CAS 1197-18-8 Tranexamic Acid

Tranexamic Acid
(CAS: 1197-18-8)

Tranexamic Acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Cefiderocol
(CAS: 1225208-94-5)

This active molecular is a potent cephalosporin antibiotic with a catechol moiety on the 3-position side chain under the development of Shionogi. Cefiderocol ex...

CAS 1093069-32-9 JNJ-39327041

JNJ-39327041
(CAS: 1093069-32-9)

JNJ-39327041 is a bio-active chemical compound.

CAS 118525-35-2 Sagittatoside A

Sagittatoside A
(CAS: 118525-35-2)

Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo.

CAS 497-76-7 Arbutin

Arbutin
(CAS: 497-76-7)

Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos. It inhibits tyrosinase and thus prevents the...

CAS 112887-68-0 Raltitrexed

Raltitrexed
(CAS: 112887-68-0)

Raltitrexed is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.

CAS 25990-60-7 Xylose

Xylose
(CAS: 25990-60-7)

Xylose is a sugar first isolated from wood.

CAS 58186-27-9 Idebenone

Idebenone
(CAS: 58186-27-9)

Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.

CP-744809
(CAS: 463976-07-0)

CP-744809 is a highly selective orally available small molecule inhibitor of aldose reductase.

CAS 122008-78-0 Cyhalofop

Cyhalofop
(CAS: 122008-78-0)

Cyhalofop(Cyhalofop acid) is a recently registered herbicide from the aryloxyphenoxy propionate group in India to control a wide range of grass weed species at ...

CP-608039
(CAS: 331727-55-0)

CP-608039 is a selective adenosine A3 receptor agonist with 1,260-fold selectivity for the human A3 versus human A1 receptor.

CAS 141993-70-6 Eldacimibe

Eldacimibe
(CAS: 141993-70-6)

Eldacimibe is a Sterol O-acyltransferase inhibitor originated by Wyeth. No development was reported for Atherosclerosis and Hypercholesterolaemia in USA.

CAS 1256094-72-0 AI-10-49

AI-10-49
(CAS: 1256094-72-0)

AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.

UK-371804
(CAS: 256477-09-5)

UK-371804 is a novel and selective inhibitors of urokinase plasminogen activator (uPA). UK-371804 exhibits excellent enzyme potency (Ki 10 nM) and selectivity p...

CAS 129558-76-5 Tolfenpyrad

Tolfenpyrad
(CAS: 129558-76-5)

Tolfenpyrad is used as foliar insecticide for the control of green peach aphids in broccoli.

CAS 199666-03-0 Ro 61-8048

Ro 61-8048
(CAS: 199666-03-0)

Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain ba...

CAS 123-82-0 2-Aminoheptane

2-Aminoheptane
(CAS: 123-82-0)

2-Aminoheptane, a fatty Amine compound, is commonly used in proteomics research and could also be used to product some A3 adenosine receptor antagonists.

LY-195448
(CAS: 111112-18-6)

LY-195448 is a phenethanolamine. It blocks cells at metaphase. It has shown anti-tumour activity.

Chemical Structure

CAS 1800025-30-2 MGAT2-IN-1

Quick Inquiry

Verification code

Featured Items