MGAT2-IN-1 - CAS 1800025-30-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H21ClF5N7O3S
Molecular Weight:
654.01
COA:
Inquire
Targets:
Others
Description:
An orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) (IC50= 7.8 for human, and 2.4 nM for mouse MGAT2).
Publictions citing BOC Sciences Products
  • >> More
Synonyms:
N-(4-chloro-2,6-difluorophenyl)-1-[5-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]pyrimidin-2-yl]-7-(2-oxopyrrolidin-1-yl)-2,3-dihydroindole-5-sulfonamide
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
838.7±75.0 ℃ at 760 Torr
Density:
1.66±0.1 g/cm3
InChIKey:
VSZRYLHBOKTNBO-UHFFFAOYSA-N
InChI:
1S/C27H21ClF5N7O3S/c1-38-20(11-22(36-38)27(31,32)33)15-12-34-26(35-13-15)40-6-4-14-7-17(10-21(25(14)40)39-5-2-3-23(39)41)44(42,43)37-24-18(29)8-16(28)9-19(24)30/h7-13,37H,2-6H2,1H3
Canonical SMILES:
CN1C(=CC(=N1)C(F)(F)F)C2=CN=C(N=C2)N3CCC4=CC(=CC(=C43)N5CCCC5=O)S(=O)(=O)NC6=C(C=C(C=C6F)Cl)F
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 406-90-6 Flurossene

Flurossene
(CAS: 406-90-6)

Fluroxene is a volatile, inhalational anesthetic, and was the first halogenated hydrocarbon anesthetic to be introduced.

CAS 23288-49-5 Probucol

Probucol
(CAS: 23288-49-5)

Enhances selective uptake of HDL-associated cholesteryl esters.

Canfosfamide Hydrochloride
(CAS: 439943-59-6)

Canfosfamide is a modified glutathione analogue as a small-molecule antineoplastic compound with potential antineoplastic activity. Canfosfamide is selectively ...

CAS 120279-96-1 Dorzolamide

Dorzolamide
(CAS: 120279-96-1)

Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to ...

LY 140091
(CAS: 74814-56-5)

LY 140091 is a bio-active chemical, but no detailed information has been published yet.

CP-67804
(CAS: 103978-08-1)

CP-67804 enhances topoisomerase II-mediated DNA cleavage. It represent a novel class of topoisomerase II-targeted drugs which have potential as antineoplastic a...

CAS 17974-57-1 β-Apo-13-carotenone

β-Apo-13-carotenone
(CAS: 17974-57-1)

β-Apo-13-carotenone, also known as D'Orenone, a naturally occurring β-apocarotenoid, is an antagonist of RXRα.

CAS 329216-63-9 Quetiapine metabolite Quetiapine sulfoxide

Quetiapine metabolite Quetiapine sulfoxi
(CAS: 329216-63-9)

Quetiapine metabolite Quetiapine sulfoxide, a metabolite of Quetiapine, has antipsychotic effect.

ZGN-839

ZGN-839 is a reversible methionine aminopeptidase 2 inhibitor developed by Zafgen that has the potential to treat nonalcoholic steatohepatitis (NASH).

CAS 93565-01-6 MDL 72527

MDL 72527
(CAS: 93565-01-6)

MDL 72527 is a polyamine oxidase inhibitor. It can block the production of H2O2 and increase the cells survival. MDL 72527 shows anticancer and neuroprotective ...

CAS 16051-77-7 Isosorbide mononitrate

Isosorbide mononitrate
(CAS: 16051-77-7)

A coronary vasodilator that does not require hepatic biotransformation

CAS 133156-06-6 GR 73632

GR 73632
(CAS: 133156-06-6)

GR 73632 is a potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). GR 73632 is able to be used in the treatment of ast...

CAS 100557-06-0 AR12456

AR12456
(CAS: 100557-06-0)

AR12456 is a trapidil derivative. It could protect against serum hyperlipidemia in guinea pigs. It has a strong antilipidemic action in guinea pigs fed a choles...

CAS 140898-91-5 Hexyl 5-aminolevulinate

Hexyl 5-aminolevulinate
(CAS: 140898-91-5)

MK-7145 dihydrochloride
(CAS: 1255204-85-3)

NS-2214
(CAS: 171655-92-8)

NS-2214, an azabicyclo compound, has been found to be a dopamine uptake inhibitor that was once studied in the treatment of Parkinson's disease.

CAS 99420-15-2 BTZO 1

BTZO 1
(CAS: 99420-15-2)

BTZO 1 is a macrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM). BTZO 1 activates antioxidant response element (ARE)-mediated gene expression and...

CAS 11027-63-7 Agnuside

Agnuside
(CAS: 11027-63-7)

Agnuside is an iridoid glycoside found in the herbs of Vitex agnus-castus, a plant native to the Mediterranean region. It is the ester of aucubin and p-hydroxyb...

ABT116
(CAS: 1008529-42-7)

ABT116 is an antagonist of transient receptor potential vanilloid type 1.

Z-Ile-Glu-Pro-Phe-Ome
(CAS: 252557-97-4)

Z-Ile-Glu-Pro-Phe-Ome is a peptide inhibitor of human heart chymase which is a chymotrypsin-like enzyme that converts angiotensin I to angiotensin II.

Chemical Structure

CAS 1800025-30-2 MGAT2-IN-1

Quick Inquiry

Verification code

Featured Items