MG-132(S,R,S) - CAS 1211877-36-9
Category: Inhibitor
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Molecular Formula:
C26H41N3O5
Molecular Weight:
475.62
COA:
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Targets:
Proteasome
Description:
MG-132(S,R,S) is a reversible, cell permeable and selective tripeptide aldehyde proteasome inhibitor (IC50 = 0.22 μM), the most potent stereoisomer of MG-132. It exhibits cytostatic and cytotoxic effects in tumor cells in vitro.
Brife Description:
A reversible, cell permeable and selective tripeptide aldehyde proteasome inhibitor (IC50 = 0.22 μM)
Purity:
99.76 %
Appearance:
White powder
Synonyms:
(R)-MG132; (R)-MG 132; (R)-MG-132; CHEMBL1090713; SCHEMBL14579851; MolPort-009-019-420; KS-000006AS; N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide
Solubility:
DMSO Solubility: 95 mg/mL (199.73 mM)
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
682.0±55.0 °C | Condition: Press: 760 Torr
Density:
1.073±0.06 g/cm3
InChIKey:
TZYWCYJVHRLUCT-ZRBLBEILSA-N
InChI:
InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22+,23-/m0/s1
Canonical SMILES:
CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
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Chemical Structure

CAS 1211877-36-9 MG-132(S,R,S)

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