MF592 - CAS 1064195-48-7
Catalog number:
1064195-48-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C34H33Cl2N3O6S
Molecular Weight:
682.61
COA:
Inquire
Targets:
Prostaglandin Receptor
Description:
MF592 is a potent and selective antagonists of the EP4 receptor. It has good functional potency and potent inhibition of PGE2 modulated TNFa release in LPS stimulated human whole blood (hWB). It displays an excellent oral pharmacokinetic (PK) profile and in vivo efficacy in a rat chronic adjuvant-induced-arthritis model. It has a desirable overall preclinical profile that suggests it is suitable for further development.
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
MF-592;2,6-Dichloro-N-((1-(4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)-3-methylbenzyl)cyclopropyl)carbamoyl)benzenesulfonamide
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Density:
1.46±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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