Methylprednisolone - CAS 83-43-2
Catalog number: 83-43-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H30O5
Molecular Weight:
374.47
COA:
Inquire
Targets:
Glucocorticoid Receptor
Description:
Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
Synonyms:
SKF 14463
MSDS:
Inquire
1.A comparative evaluation of the effect of diclofenac sodium with and without per-orally administered methylprednisolone on the sequelae of impacted mandibular third molar removal: A cohort randomized double-blind clinical trial.
Prashar DV1, Pahwa D2, Kalia V2, Jindal G3, Kaur R4. Indian J Dent. 2016 Jan-Mar;7(1):11-6. doi: 10.4103/0975-962X.158187.
AIM AND OBJECTIVES: This study evaluated the efficacy of oral methylprednisolone and diclofenac sodium on post-operative sequelae after third molar surgery.
2.Relationship between magnetic resonance imaging signal intensity and volume of extraocular muscles in thyroid-associated ophthalmopathy with methylprednisolone pulse therapy.
Higashiyama T1, Nishida Y2, Ohji M1. Clin Ophthalmol. 2016 Apr 20;10:721-9. doi: 10.2147/OPTH.S105096. eCollection 2016.
PURPOSE: To characterize the relationship between inflammation and swelling of extraocular muscles in thyroid-associated ophthalmopathy before and after methylprednisolone pulse therapy.
3.Clinical experience with repository corticotropin injection in patients with multiple sclerosis experiencing mood changes with intravenous methylprednisolone: a case series.
Murray S1, Woo A2. Ther Adv Neurol Disord. 2016 May;9(3):189-97. doi: 10.1177/1756285615618642. Epub 2015 Dec 7.
The elevated prevalence of neuropsychiatric symptoms and disorders among patients with multiple sclerosis (MS) is well recognized, as are potential neuropsychiatric side effects of treatment with corticosteroids. Both methylprednisolone (MP) and repository corticotropin injection (HP Acthar(®) gel) have demonstrated efficacy in reducing short-term disability after exacerbations of MS. Although historical data are limited, repository corticotropin injection has not generally been associated with detrimental neuropsychiatric effects. We describe six cases of patients with relapsing-remitting MS who had previously experienced detrimental mood changes with MP treatment. Some of these patients had previous histories of mood disorders or other neuropsychiatric symptoms prior to MS diagnosis. All six patients were subsequently treated with repository corticotropin injection for MS exacerbations and each demonstrated improvements in MS symptoms.
4.Posturography in MS patients treated with high dose methylprednisolone.
Gandelman-Marton R1, Arlazoroff A1, Dvir Z2. Neurol Res. 2016 May 6:1-5. [Epub ahead of print]
OBJECTIVES: To evaluate the sensitivity of the balance sway index (SI) to drug-induced functional changes during acute relapse in patients with MS.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Glucocorticoid Receptor Products


CAS 152-58-9 Cortodoxone

Cortodoxone
(CAS: 152-58-9)

Cortodoxone, a glucocorticoid receptor antagonist, is an intermediate which can be oxygenated to cortisol.

CAS 124-94-7 Triamcinolone

Triamcinolone
(CAS: 124-94-7)

Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topic...

CAS 83919-23-7 Mometasone furoate

Mometasone furoate
(CAS: 83919-23-7)

Mometasone furoate, prodrug of the free form mometasone, is an agent with high affinity for the glucocorticoid receptor with anti-allergic property. It can be u...

CAS 50-02-2 Dexamethasone

Dexamethasone
(CAS: 50-02-2)

Dexamethasone is a glucocorticoid with anti-inflammatory activity that reduces levels of activated NF-κB in immature dendritic cells (DCs) and inhibits differen...

CAS 378-44-9 Betamethasone

Betamethasone
(CAS: 378-44-9)

Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone d...

AL 082D06
(CAS: 256925-03-8)

AL 082D06, also called as D-06, is a selective nonsteroidal antagonist of glucocorticoid receptor (GR) (Ki= 210 nM) without significant activity on AR, PR, MR a...

CAS 3385-03-3 Flunisolide Hemihydrate

Flunisolide Hemihydrate
(CAS: 3385-03-3)

Flunisolide, a kind of corticosteroid compound, often being used against allergic rhinitis by activating glucocorticoid receptors. It was also found that it mig...

CAS 51333-22-3 Budesonide

Budesonide
(CAS: 51333-22-3)

Budesonide is a glucocorticoid steroid that activates the glucorcorticoid receptor with an EC50 value of 12.4 nM. Like other glucocorticoids, budesonide reduces...

CAS 14484-47-0 Deflazacort

Deflazacort
(CAS: 14484-47-0)

Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.

CAS 83-43-2 Methylprednisolone

Methylprednisolone
(CAS: 83-43-2)

Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.

CAS 22427-39-0 Ginsenoside Rg1

Ginsenoside Rg1
(CAS: 22427-39-0)

Ginsenoside Rg1 is extrected from the roots of Panax ginseng C. A. Mey. It has estrogen-like activity and should be classified as a novel class of potent phytoe...

CAS 397864-44-7 Fluticasone furoate

Fluticasone furoate
(CAS: 397864-44-7)

Fluticasone furoate is a synthetic corticosteroid derived from fluticasone as a selective high affinity glucocorticoid agonist, MRP4 inhibitor;

CAS 50-24-8 Prednisolone

Prednisolone
(CAS: 50-24-8)

Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.

CAS 51022-69-6 Amcinonide

Amcinonide
(CAS: 51022-69-6)

Amcinonide is a corticosteroid (IC50=3.38 nM) used as anti-inflammatory and antipruritic agents.

CAS 1177-87-3 Dexamethasone Acetate

Dexamethasone Acetate
(CAS: 1177-87-3)

The acetate-protect form of Dexamethasone which is a glucocorticoid and could be used as a anti-inflammatory agent.

CAS 1245526-82-2 Glucocorticoid receptor agonist

Glucocorticoid receptor agonist
(CAS: 1245526-82-2)

Glucocorticoid receptor agonist is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties.

CAS 125-02-0 Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate
(CAS: 125-02-0)

The disodium phosphate salt form of Prednisolone which has anti-inflammatory and immunsuppressive effect for behaving as a glucocorticoid.

CAS 5534-09-8 Beclomethasone dipropionate

Beclomethasone dipropionate
(CAS: 5534-09-8)

Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.

Betamethasone hydrochloride
(CAS: 956901-32-9)

Betamethasone hydrochloride is the hydrochloride of betamethasone, which is a synthetic corticosteroid and agonist of glucocorticoid receptor. It does not cause...

CAS 50-04-4 Cortisone acetate

Cortisone acetate
(CAS: 50-04-4)

Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.

Chemical Structure

CAS 83-43-2 Methylprednisolone

Quick Inquiry

Verification code

Featured Items