Methylprednisolone - CAS 83-43-2
Catalog number: 83-43-2
Category: Inhibitor
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Molecular Formula:
Molecular Weight:
Glucocorticoid Receptor
Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
SKF 14463; SKF14463; SKF-14463; Methylprednisolone, Medrol, Solu-Medrol, Metipred, Urbason
Canonical SMILES:
1.A comparative evaluation of the effect of diclofenac sodium with and without per-orally administered methylprednisolone on the sequelae of impacted mandibular third molar removal: A cohort randomized double-blind clinical trial.
Prashar DV1, Pahwa D2, Kalia V2, Jindal G3, Kaur R4. Indian J Dent. 2016 Jan-Mar;7(1):11-6. doi: 10.4103/0975-962X.158187.
AIM AND OBJECTIVES: This study evaluated the efficacy of oral methylprednisolone and diclofenac sodium on post-operative sequelae after third molar surgery.
2.Relationship between magnetic resonance imaging signal intensity and volume of extraocular muscles in thyroid-associated ophthalmopathy with methylprednisolone pulse therapy.
Higashiyama T1, Nishida Y2, Ohji M1. Clin Ophthalmol. 2016 Apr 20;10:721-9. doi: 10.2147/OPTH.S105096. eCollection 2016.
PURPOSE: To characterize the relationship between inflammation and swelling of extraocular muscles in thyroid-associated ophthalmopathy before and after methylprednisolone pulse therapy.
3.Clinical experience with repository corticotropin injection in patients with multiple sclerosis experiencing mood changes with intravenous methylprednisolone: a case series.
Murray S1, Woo A2. Ther Adv Neurol Disord. 2016 May;9(3):189-97. doi: 10.1177/1756285615618642. Epub 2015 Dec 7.
The elevated prevalence of neuropsychiatric symptoms and disorders among patients with multiple sclerosis (MS) is well recognized, as are potential neuropsychiatric side effects of treatment with corticosteroids. Both methylprednisolone (MP) and repository corticotropin injection (HP Acthar(®) gel) have demonstrated efficacy in reducing short-term disability after exacerbations of MS. Although historical data are limited, repository corticotropin injection has not generally been associated with detrimental neuropsychiatric effects. We describe six cases of patients with relapsing-remitting MS who had previously experienced detrimental mood changes with MP treatment. Some of these patients had previous histories of mood disorders or other neuropsychiatric symptoms prior to MS diagnosis. All six patients were subsequently treated with repository corticotropin injection for MS exacerbations and each demonstrated improvements in MS symptoms.
4.Posturography in MS patients treated with high dose methylprednisolone.
Gandelman-Marton R1, Arlazoroff A1, Dvir Z2. Neurol Res. 2016 May 6:1-5. [Epub ahead of print]
OBJECTIVES: To evaluate the sensitivity of the balance sway index (SI) to drug-induced functional changes during acute relapse in patients with MS.
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CAS 83-43-2 Methylprednisolone

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