Methylprednisolone - CAS 83-43-2
Catalog number: 83-43-2
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C22H30O5
Molecular Weight:
374.47
COA:
Inquire
Targets:
Glucocorticoid Receptor
Description:
Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
Purity:
>98%
Synonyms:
SKF 14463; SKF14463; SKF-14463; Methylprednisolone, Medrol, Solu-Medrol, Metipred, Urbason
MSDS:
Inquire
InChIKey:
VHRSUDSXCMQTMA-PJHHCJLFSA-N
InChI:
InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1
Canonical SMILES:
CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
1.A comparative evaluation of the effect of diclofenac sodium with and without per-orally administered methylprednisolone on the sequelae of impacted mandibular third molar removal: A cohort randomized double-blind clinical trial.
Prashar DV1, Pahwa D2, Kalia V2, Jindal G3, Kaur R4. Indian J Dent. 2016 Jan-Mar;7(1):11-6. doi: 10.4103/0975-962X.158187.
AIM AND OBJECTIVES: This study evaluated the efficacy of oral methylprednisolone and diclofenac sodium on post-operative sequelae after third molar surgery.
2.Relationship between magnetic resonance imaging signal intensity and volume of extraocular muscles in thyroid-associated ophthalmopathy with methylprednisolone pulse therapy.
Higashiyama T1, Nishida Y2, Ohji M1. Clin Ophthalmol. 2016 Apr 20;10:721-9. doi: 10.2147/OPTH.S105096. eCollection 2016.
PURPOSE: To characterize the relationship between inflammation and swelling of extraocular muscles in thyroid-associated ophthalmopathy before and after methylprednisolone pulse therapy.
3.Clinical experience with repository corticotropin injection in patients with multiple sclerosis experiencing mood changes with intravenous methylprednisolone: a case series.
Murray S1, Woo A2. Ther Adv Neurol Disord. 2016 May;9(3):189-97. doi: 10.1177/1756285615618642. Epub 2015 Dec 7.
The elevated prevalence of neuropsychiatric symptoms and disorders among patients with multiple sclerosis (MS) is well recognized, as are potential neuropsychiatric side effects of treatment with corticosteroids. Both methylprednisolone (MP) and repository corticotropin injection (HP Acthar(®) gel) have demonstrated efficacy in reducing short-term disability after exacerbations of MS. Although historical data are limited, repository corticotropin injection has not generally been associated with detrimental neuropsychiatric effects. We describe six cases of patients with relapsing-remitting MS who had previously experienced detrimental mood changes with MP treatment. Some of these patients had previous histories of mood disorders or other neuropsychiatric symptoms prior to MS diagnosis. All six patients were subsequently treated with repository corticotropin injection for MS exacerbations and each demonstrated improvements in MS symptoms.
4.Posturography in MS patients treated with high dose methylprednisolone.
Gandelman-Marton R1, Arlazoroff A1, Dvir Z2. Neurol Res. 2016 May 6:1-5. [Epub ahead of print]
OBJECTIVES: To evaluate the sensitivity of the balance sway index (SI) to drug-induced functional changes during acute relapse in patients with MS.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Glucocorticoid Receptor Products


CAS 5534-09-8 Beclomethasone dipropionate

Beclomethasone dipropionate
(CAS: 5534-09-8)

Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.

CAS 126544-47-6 Ciclesonide

Ciclesonide
(CAS: 126544-47-6)

Ciclesonide, a glucocorticoid, could be useful in the treatment of sorts of airway inflammatory diseases like allergic rhinitis.

CAS 1177-87-3 Dexamethasone Acetate

Dexamethasone Acetate
(CAS: 1177-87-3)

The acetate-protect form of Dexamethasone which is a glucocorticoid and could be used as a anti-inflammatory agent.

CAS 3385-03-3 Flunisolide

Flunisolide
(CAS: 3385-03-3)

Flunisolide is a corticosteroid and used for the treatment of allergic rhinitis.

CAS 50-04-4 Cortisone acetate

Cortisone acetate
(CAS: 50-04-4)

Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.

CAS 1044535-58-1 PF-04171327

PF-04171327
(CAS: 1044535-58-1)

PF-04171327 is a dissociated agonist of the glucocorticoid receptor (DAGR), which is a selective high-affinity partial agonist of the GR. It has potent anti-inf...

CAS 84371-65-3 Mifepristone

Mifepristone
(CAS: 84371-65-3)

Mifepristone is a progesterone receptor antagonist(IC50= 0.2 nM) and a glucocorticoid receptor antagonist(IC50= 2.6 nM). It is used as an abortifacient in the f...

CAS 50-02-2 Dexamethasone

Dexamethasone
(CAS: 50-02-2)

Dexamethasone is a glucocorticoid with anti-inflammatory activity that reduces levels of activated NF-κB in immature dendritic cells (DCs) and inhibits differen...

Chemical Structure

CAS 83-43-2 Methylprednisolone

Quick Inquiry

Verification code

Featured Items