αβ-methylene ATP - CAS 1343364-54-4
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C11H15N5Na3O12P3
Molecular Weight:
571.15
COA:
Inquire
Targets:
P2Y Receptor
Description:
αβ-methylene ATP, a phosphonic analog of ATP, is an agonist of P2X purinoceptors P2X1 and P2X3 (EC50 = ~1 µM) and is ~1,000-fold less potent at P2X2, P2X receptors 4-7, and P2Y receptors. αβ-methylene ATP also appears to act as an antagonist against endogenously released adenine nucleosides and nucleotides.
Purity:
≥98% by HPLC
Synonyms:
α,β-Methyleneadenosine 5'-triphosphate trisodium salt; α,β-Methyleneadenosine 5'-triphosphate trisodium salt; alpha,beta-methylene Adenosine 5'-triphosphate (sodium salt)
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
CBAGKCWFSRTVER-MTQUBGKESA-K
InChI:
InChI=1S/C11H18N5O12P3.3Na/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-29(19,20)4-30(21,22)28-31(23,24)25;;;/h2-3,5,7-8,11,17-18H,1,4H2,(H,19,20)(H,21,22)(H2,12,13,14)(H2,23,24,25);;;/q;3*+1/p-3/t5-,7-,8-,11-;;;/m1.../s1
Canonical SMILES:
C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(CP(=O)([O-])OP(=O)(O)[O-])[O-])O)O.[Na+].[Na+].[Na+]
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related P2Y Receptor Products


CAS 216657-60-2 AR-C 118925XX

AR-C 118925XX
(CAS: 216657-60-2)

AR-C126313, a thiouracil derivative, has been found to be a competitive P2Y2 receptor antagonist and could inhibit P2Y2 receptor-induced β-arrestin translocatio...

CAS 56583-49-4 PIT

PIT
(CAS: 56583-49-4)

PIT selectively and non-competitively blocked P2Y1 receptor signaling without affecting nucleotide binding. PIT had no significant effect on agonist activation ...

CAS 1266569-94-1 UTPγS trisodium salt

UTPγS trisodium salt
(CAS: 1266569-94-1)

UTPγS trisodium salt is a selective P2Y2 and P2Y4 receptor agonist.

CAS 1279829-64-9 SAR 216471 hydrochloride

SAR 216471 hydrochloride
(CAS: 1279829-64-9)

SAR 216471 hydrochloride is a potent and reversible P2Y12 antagonist (IC50 = 17 nM), displaying antiplatelet and antithrombotic activity in vivo.

CAS 1006028-37-0 NF 546

NF 546
(CAS: 1006028-37-0)

NF 546 is a P2Y11 agonist with pEC50 value of 6.27. It can stimulate release of interleukin-8 from human monocyte-derived dendritic cells.

CAS 711019-86-2 MRS 2578

MRS 2578
(CAS: 711019-86-2)

MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.

CAS 1228271-30-4 MRS 2957 triethylammonium salt

MRS 2957 triethylammonium salt
(CAS: 1228271-30-4)

MRS 2957 triethylammonium salt 7 is a selective P2Y6 receptor agonists (EC50 = 12 nM) for the treatment of muscle wasting and neurodegeneration. It exhibits 14-...

CAS 1343364-70-4 2-ThioUTP tetrasodium salt

2-ThioUTP tetrasodium salt
(CAS: 1343364-70-4)

2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist (EC50 = 0.035, 0.35 and 1.5 μM for hP2Y2, hP2Y4 and hP2Y6 receptors, respectively).

Chemical Structure

CAS 1343364-54-4 αβ-methylene ATP

Quick Inquiry

Verification code

Featured Items