|Description||Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.|
MK-351 hydrochloride is an alpha-adrenergic agonist selective for α2-adrenergic receptors. It is a psychoactive drug used as a sympatholytic or antihypertensive...
Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.
A potent dual antagonist of α1-adrenergic receptor and 5-HT2 receptor
ABT-866 is a novel alpha-adrenoceptor agent that demonstrates intrinsic activity at the α1A-adrenoceptor subtype present in the rabbit urethra (pD2=6.22, with 8...
Levobetaxolol exhibits a higher affinity at cloned human β1 and β2 receptors with Ki value of 0.76 nM and 32.6 nM, respectively.
Prazosin HCl, a quinazoline derivative, is the first of a new chemical class of antihypertensives.
Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.
This active molecular is a selective α1D Adrenergic Receptor antagonist. ( Ki value of 1.1 nM, 200 fold selective over α1A and 800 fold selective over α1B). TAK...
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn..
B-HT 920 dihydrochloride
Talipexole is a D2 dopamine receptor agonist, displaying anti-Parkinsonian activity.
Batefenterol is a Beta 2 adrenergic receptor agonist and also a Muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic rec...
GYKI-16084 is a postsynaptic alpha2-blocker with the potential to treat benign prostatic hyperplasia.
Arbutamine is β-adrenergic receptor originated by SICOR. It is a cardiac stimulant. Arbutamine is a synthetic catecholamine with positive chronotropic and inotr...
Tamsulosin could block on the sympathetic α1 receptor, especially selectively bind to the α1A receptor and has been found to be effective in the treatment of be...
Yohimbine, an indolalkylamine alkaloid, blocks presynaptic alpha-2 adrenergic receptors. IC50= 0.6 μM Ki: 1.05 nM, alphaα2Areceptor
Fenoterol hydrobromide is a β2-adrenergic agonist agent used for asthma and chronic obstructive pulmonary disease treatment. It has already been approved for us...
Phenylephrine HCl is a selective α1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, a...
Terazosin, works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls, is a selective alpha1-antagonist used for trea...
Octopamine hydrochloride is an α-adrenoceptor agonist.
Pindolol, an Indole derivative, could be used in the treatment of hypertension and arrhythmia for acting as a 5-HT1A/1B receptor antagonist. IC50: 33nM(Ki).