Methocarbamol - CAS 532-03-6
Catalog number: 532-03-6
Category: Inhibitor
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Molecular Formula:
Molecular Weight:
Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.
AHR 85; AHR85; AHR-85
Canonical SMILES:
1.Muscle relaxants--the current position in the treatment of spasticity in orthopedics.
Zygmunt M1, Sapa J1. Ortop Traumatol Rehabil. 2015 Jul-Aug;17(4):423-30. doi: 10.5604/15093492.1173500.
Muscle tone often exists concomitantly with pain symptoms in different neurological and orthopaedic disease entities. In order to overcome that painful symptom, it is crucial to integrate painkillers with adjunctive therapy using muscle relaxants which decrease the muscle tone. Muscle relaxants available in pharmaceutical trade suppress motor outflow through different mechanisms of action, these include drugs such as: Tizanidine, botulinum toxin, Baclofen, Tolperisone, Methocarbamol. Combining muscle relaxants with analgesics significantly improves the effectiveness of the treatment and allows to reduce drugs doses.
2.[Methocarbamol in acute low back pain. A randomized double-blind controlled study].
Emrich OM1, Milachowski KA, Strohmeier M. MMW Fortschr Med. 2015 Jul;157 Suppl 5:9-16. doi: 10.1007/s15006-015-3307-x. Epub 2015 Jul 13.
BACKGROUND: Muscle relaxants are widely used to treat low back pain (LBP), one of the most frequent health problems in industrialized countries. For this indication, the European Medicines Agency (EMA) recently had imposed restrictions for some muscle relaxants, anti-inflammatories and analgesics; Tetrazepam even had to be withdrawn from the market. Therefore methocarbamol remains the only approved muscle relaxant. Methocarbamol is well-established for the treatment of LBP associated with myofascial components, although more recent clinical studies have not been published. Therefore this publication summarizes and revaluates post-hoc data of an efficiency study of methocarbamol, that was performed in 2002, but had not been published yet.
3.Anticholinergic Risk and Frequency of Anticholinergic Drug Prescriptions in a Population Older Than 65.
Machado-Alba JE1, Castro-Rodríguez A2, Álzate-Piedrahita JA3, Hoyos-Pulgarín JA3, Medina-Morales DA4. J Am Med Dir Assoc. 2016 Mar 1;17(3):275.e1-4. doi: 10.1016/j.jamda.2015.12.003. Epub 2016 Jan 18.
OBJECTIVE: To determine the risk and frequency of anticholinergic drug prescriptions in a population affiliated with the Colombian General System of Social Security in Health.
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CAS 532-03-6 Methocarbamol

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