|Description||Methimazole inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I−) to iodine (I2), hypoiodous acid (HOI), enzyme linked hypoiodate (EOI) facilitating iodine's addition to tyrosine residues on the hormone precursor thyroglobulin, a necessary step in the synthesis of triiodothyronine (T3) and thyroxine (T4).|
|Solubility||well in acetic acid; moderately in chloroform; practically not in 95% ethanol and water.|
|Storage||Stable in dry state; store at 4 °C, in dark place.|
|Melting Point||195-198 °C|
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