Methenolone acetate - CAS 434-05-9
Catalog number: 434-05-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H32O3
Molecular Weight:
344.49
COA:
Inquire
Targets:
Others
Description:
Metenolone enanthate,is a dihydrotestosterone based anabolic steroid with weak androgenic properties.
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Purity:
≥98 %
Appearance:
White solid
Synonyms:
17-(acetyloxy)-1-methyl-,(5-alpha,17-beta)-androst-1-en-3-on;17-beta-hydroxy-1-methyl-5-alpha-androst-1-en-3-onacetate;17-beta-hydroxy-1-methyl-5-alpha-androst-1-en-3-oneacetate;
Solubility:
Soluble in DMSO
Storage:
Store at 2-8 °C
MSDS:
Inquire
Application:
Anabolic steroid
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Grams-Kilos
Density:
1.1 g/cm3
InChIKey:
PGAUJQOPTMSERF-QWQRBHLCSA-N
InChI:
1S/C22H32O3/c1-13-11-16(24)12-15-5-6-17-18-7-8-20(25-14(2)23)21(18,3)10-9-19(17)22(13,15)4/h11,15,17-20H,5-10,12H2,1-4H3/t15-,17-,18-,19-,20-,21-,22-/m0/s1
Canonical SMILES:
CC1=CC(=O)CC2C1(C3CCC4(C(C3CC2)CCC4OC(=O)C)C)C
1.Screening of anabolic steroids in horse urine by liquid chromatography-tandem mass spectrometry.
Yu NH1, Ho EN, Leung DK, Wan TS. J Pharm Biomed Anal. 2005 Apr 29;37(5):1031-8.
Anabolic steroids have the capability of improving athletic performance and are banned substances in the Olympic games as well as in horseracing and equestrian competitions. The control of their abuse in racehorses is traditionally performed by detecting the presence of anabolic steroids and/or their metabolite(s) in urine samples using gas chromatography-mass spectrometry (GC-MS). However, this approach usually requires tedious sample processing and chemical derivatisation steps and could be very insensitive in detecting certain steroids. This paper describes a high performance liquid chromatography-tandem mass spectrometry (HPLC-MS-MS) method for the detection of anabolic steroids that are poorly covered by GC-MS. Enzyme-treated urine was processed by solid-phase extraction (SPE) using a Bond Elut Certify cartridge, followed by a base wash for further cleanup. Separation of the steroids was carried out on a reversed-phase DB-8 column using 0.
2.[Hemophagocytic syndrome due to miliary tuberculosis in the course of aplastic anemia].
Yashima A1, Narigasawa Y, Ishida Y, Uchiyama T, Oyake T, Enomoto S, Kaneko J, Ono Y, Sugawara T, Numaoka H, Shimosegawa K, Murai K, Itoh S, Ito T, Kuriya S. Rinsho Ketsueki. 1998 May;39(5):392-7.
We report a 63 year-old female with aplastic anemia (AA) who was complicated with hemophagocytic syndrome induced by systemic miliary tuberculosis. Two years before admission to our hospital, she was diagnosed as AA and had been treated with granulocyte colony-stimulating factor, erythropoietin and methenolone acetate. In May, 1996, She was transferred to our hospital because of high fever and exacervation of pancytopenia. She showed severe pancytopenia, and an increase in macrophages showing remarkable erythrophagocytosis and decrease in hemopoietic cells in the bone marrow. In initial examination, high titer of IgM antibody to herpes simplex virus type I was identified and methylprednisolone pulse therapy was started under the diagnosis of virus associated hemophagocytic syndrome. Ten days later, however, she died for intestinal hemorrhage followed by multiorgan failure. In autopsy, multiple epitheloid cell granulomas with acid-fast bacilli were found in bone marrow, lungs, liver, spleen and kidneys.
3.Endocrinological and pathological effects of anabolic-androgenic steroid in male rats.
Takahashi M1, Tatsugi Y, Kohno T. Endocr J. 2004 Aug;51(4):425-34.
Many athletes use drugs, especially anabolic androgenic steroids (AAS), but there are few reports on the endocrinological and pathological changes in AAS abusers. In this study we reported the results of endocrinological examinations in rats administered AAS and also physical changes. We separated 37 male Wistar rats (7 weeks old) into 3 groups: Group A was medicated with nandrolone decanoate, metenolone acetate, and dromostanolone; Group B with nandrolone decanoate and saline; and Group C was given only saline. They were given subcutaneous injections of the medications or the control vehicle once a week for 6 weeks. Medications were stopped for 4 weeks, and then resumed for another 6 weeks. After that, rats were sacrificed. Serum testosterone level in Group A was significantly higher than that in Group C. Serum dihydrotestosterone in Group A was significantly higher than that in both Groups B and C. Serum estradiol-17beta levels in Groups A and B were significantly higher than that in Group C.
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Chemical Structure

CAS 434-05-9 Methenolone acetate

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