|Description||Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.|
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A potent medium-lasting selective M2 muscarinic receptor antagonist.
Hyoscyamine is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, non-selective antagonist at Muscarinic recepto...
A microtubule-disrupting agent.
Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic ...
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Norfluorocurarine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) .<br/>Generic drugs containing vincam...
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Quinoline alkaloid, extracted from Haplophyllum bucharicum (Rutacae)
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab ma...
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
[Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. , synthetic, originally from Leiurus quinquestriatus hebr...
Complex of lanthanide element,an anticoagulant. The lanthanide element from Glutasam replaces calcium in its complex with prothrombine, thus preventing the form...
Derivative of Napelline. Napelline isolated from plant Aconitum karakolicum Diterpenoid Alkaloid Synthesized from Napelline. Napelline is extracted from Aconitu...
Steroidal Alkaloid from Convolvulus krauseanus
Anti-tumor effect of hernandezine and other components extracted from Thalictrum glandulosissimum.
Bicyclic analog of Ach, a weak muscarinic AChR agonist.
ShK – Stichodactyla toxin
ShK (Stichodactyla helianthus Neurotoxin) has been isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK inhibits voltage-dependent p...